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EPRS1 and MIR17
Data Source:
BioGRID
(unspecified method)
EPRS1
MIR17
Description
glutamyl-prolyl-tRNA synthetase 1
microRNA 17
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
GAIT Complex
Ribonucleoprotein Complex
Extracellular Space
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Glutamate-tRNA Ligase Activity
Proline-tRNA Ligase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
TRNA Aminoacylation For Protein Translation
Glutamyl-tRNA Aminoacylation
Prolyl-tRNA Aminoacylation
Negative Regulation Of Translation
Cellular Response To Insulin Stimulus
Protein-containing Complex Assembly
Cellular Response To Interferon-gamma
Regulation Of Long-chain Fatty Acid Import Into Cell
Negative Regulation Of Systemic Arterial Blood Pressure
Outflow Tract Morphogenesis
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Low-density Lipoprotein Particle Clearance
Negative Regulation Of Toll-like Receptor Signaling Pathway
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Blood Pressure
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Phagocytosis
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Positive Regulation Of Metalloendopeptidase Activity
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Apoptosome Assembly
Positive Regulation Of Pulmonary Blood Vessel Remodeling
Positive Regulation Of Smooth Muscle Hypertrophy
Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Negative Regulation Of Cellular Senescence
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
tRNA modification in the nucleus and cytosol
Drugs
Glutamic acid
Proline
5'-O-(L-Prolylsulfamoyl)adenosine
5'-O-(L-Cysteinylsulfamoyl)adenosine
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS
Interacting Genes
89 interacting genes:
AIMP2
ARL4D
CDC42
DUS2
DUX4
EEF1D
ESR1
HSP90AA1
IARS1
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NELFCD
PTEN
RARS1
SUMO2
SYNCRIP
TAB1
84 interacting genes:
AIMP1
APOBEC3B
ATXN2L
C1QBP
CELF1
CPSF6
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TRMT1L
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZNF346
Entrez ID
2058
406952
HPRD ID
00703
Ensembl ID
ENSG00000136628
ENSG00000284536
Uniprot IDs
P07814
PDB IDs
1FYJ
4HVC
4K86
4K87
4K88
5A1N
5A34
5A5H
5BMU
5V58
5VAD
5Y6L
6IY6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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