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EPRS1 and MIR206
Data Source:
BioGRID
(unspecified method)
EPRS1
MIR206
Description
glutamyl-prolyl-tRNA synthetase 1
microRNA 206
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
GAIT Complex
Ribonucleoprotein Complex
RISC Complex
Molecular Function
Glutamate-tRNA Ligase Activity
Proline-tRNA Ligase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
MRNA 3'-UTR Binding
Protein Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
TRNA Aminoacylation For Protein Translation
Glutamyl-tRNA Aminoacylation
Prolyl-tRNA Aminoacylation
Negative Regulation Of Translation
Cellular Response To Insulin Stimulus
Protein-containing Complex Assembly
Cellular Response To Interferon-gamma
Regulation Of Long-chain Fatty Acid Import Into Cell
Positive Regulation Of Cell Fate Commitment
Negative Regulation Of Gene Expression
Positive Regulation Of Myotube Differentiation
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Tumor Necrosis Factor Production
Gene Silencing By MiRNA
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Neuroinflammatory Response
Positive Regulation Of Amyloid-beta Formation
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
tRNA modification in the nucleus and cytosol
Drugs
Glutamic acid
Proline
5'-O-(L-Prolylsulfamoyl)adenosine
5'-O-(L-Cysteinylsulfamoyl)adenosine
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS
Interacting Genes
89 interacting genes:
AIMP2
ARL4D
CDC42
DUS2
DUX4
EEF1D
ESR1
HSP90AA1
IARS1
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NELFCD
PTEN
RARS1
SUMO2
SYNCRIP
TAB1
78 interacting genes:
ADARB1
AIMP1
AQR
C1QBP
CELF1
CPSF1
CSTF1
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LCORL
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
NOL4L
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUM1
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SF3A3
SF3B1
SF3B2
SF3B3
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
2058
406989
HPRD ID
00703
Ensembl ID
ENSG00000136628
ENSG00000207604
Uniprot IDs
P07814
PDB IDs
1FYJ
4HVC
4K86
4K87
4K88
5A1N
5A34
5A5H
5BMU
5V58
5VAD
5Y6L
6IY6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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