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FAM209A and AQP1
Data Source:
BioGRID
(two hybrid)
FAM209A
AQP1
Description
family with sequence similarity 209 member A
aquaporin 1 (Colton blood group)
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Integral Component Of Membrane
Extracellular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Molecular Function
Molecular_function
Protein Binding
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Biological Process
Biological_process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Heschl's gyrus morphology (
25130324
)
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
231 interacting genes:
-
ADGRE2
ADIPOQ
AGTRAP
AIG1
ALG8
ANKRD46
APMAP
APOC3
APOD
APOL2
AQP1
AQP2
AQP3
ARV1
ASGR1
ATP13A1
B4GALNT2
BDNF
BET1
BIK
BMP10
BNIP2
BNIP3
BTN2A2
C11orf24
C14orf180
C1GALT1
C2
C3orf52
C4orf3
CANT1
CCL4L2
CD53
CD59
CD81
CDIPT
CDS1
CDS2
CLCA4
CLDN19
CLDN2
CLDN4
CLDND2
CLEC4G
CLN6
CMTM7
CNIH1
CNPY3
COL4A5
COL8A2
COMT
CTRL
CTSA
CTXN3
CXCL16
CYB561D2
CYB5B
CYBC1
DEFB121
DEFB128
DNAJC30
DOLK
EBP
EMC6
EMD
ENTPD3
EOGT
ERG28
ERMP1
FA2H
FAM20B
FAM3C
FATE1
FCER1G
FDFT1
FIS1
FXYD3
GAST
GET3
GHITM
GIMAP1
GJB2
GKN1
GKN2
GOSR2
GPR108
GPR151
GPR37L1
GYPA
HACD2
HHATL
HMOX1
HMOX2
HTATIP2
IGFBP5
INSIG2
JAGN1
KIR2DL3
LHFPL5
LPAR3
LRP10
MAL
MARCHF2
MFF
MGLL
MIP
MMD
MMD2
MS4A1
MS4A13
MYADM
MYADML2
NAPB
NAT8
NCR3
NINJ2
NRM
NXPE3
OLFM4
ORMDL3
OTOR
PAQR7
PEDS1-UBE2V1
PGAP2
PGLYRP3
PLN
PLP1
PLP2
PLPP4
PLPP6
PMP22
PNLIPRP1
PRB1
PTCH1
RHAG
RPRM
RTP2
RUSF1
S100A2
SCARF1
SCGB1D1
SCRG1
SEC22A
SEC22B
SEC61G
SELENOK
SEMA6C
SERP1
SFTPC
SLC13A3
SLC1A1
SLC30A8
SLC35A1
SLC35A4
SLC35B4
SLC35E3
SLC35G2
SLC38A7
SLC52A2
SLC7A14
SMCO4
SMIM1
SNORC
STATH
STX1B
STX3
STX5
STX8
SYNGR1
SYT15
TECR
TEX264
TFRC
THBD
THSD7B
TM6SF2
TMBIM6
TMEM100
TMEM107
TMEM11
TMEM120A
TMEM128
TMEM140
TMEM141
TMEM14B
TMEM14C
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM236
TMEM243
TMEM254
TMEM42
TMEM43
TMEM47
TMEM50B
TMEM60
TMEM65
TMEM72
TMEM79
TMEM86A
TMEM86B
TMEM97
TMPRSS4
TMUB2
TNF
TNFRSF10C
TNMD
TRAF3IP3
TRAM1L1
TSPAN2
TSPAN33
TSPAN7
TSPO
TWSG1
UBE2J1
UBIAD1
UNC50
UPK1B
VAMP3
VAMP4
VAMP5
VKORC1
VMP1
WFDC2
WFS1
YIPF6
ZFPL1
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
Entrez ID
200232
358
HPRD ID
18536
00140
Ensembl ID
ENSG00000124103
ENSG00000240583
Uniprot IDs
Q5JX71
A0A024RA31
P29972
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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