FAM209A and STX5

Data Source:
BioGRID (two hybrid)

		FAM209A	STX5
Description		family with sequence similarity 209 member A	syntaxin 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Molecular_function Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Biological_process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways			COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Heschl's gyrus morphology ( 25130324)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		231 interacting genes: - ADGRE2 ADIPOQ AGTRAP AIG1 ALG8 ANKRD46 APMAP APOC3 APOD APOL2 AQP1 AQP2 AQP3 ARV1 ASGR1 ATP13A1 B4GALNT2 BDNF BET1 BIK BMP10 BNIP2 BNIP3 BTN2A2 C11orf24 C14orf180 C1GALT1 C2 C3orf52 C4orf3 CANT1 CCL4L2 CD53 CD59 CD81 CDIPT CDS1 CDS2 CLCA4 CLDN19 CLDN2 CLDN4 CLDND2 CLEC4G CLN6 CMTM7 CNIH1 CNPY3 COL4A5 COL8A2 COMT CTRL CTSA CTXN3 CXCL16 CYB561D2 CYB5B CYBC1 DEFB121 DEFB128 DNAJC30 DOLK EBP EMC6 EMD ENTPD3 EOGT ERG28 ERMP1 FA2H FAM20B FAM3C FATE1 FCER1G FDFT1 FIS1 FXYD3 GAST GET3 GHITM GIMAP1 GJB2 GKN1 GKN2 GOSR2 GPR108 GPR151 GPR37L1 GYPA HACD2 HHATL HMOX1 HMOX2 HTATIP2 IGFBP5 INSIG2 JAGN1 KIR2DL3 LHFPL5 LPAR3 LRP10 MAL MARCHF2 MFF MGLL MIP MMD MMD2 MS4A1 MS4A13 MYADM MYADML2 NAPB NAT8 NCR3 NINJ2 NRM NXPE3 OLFM4 ORMDL3 OTOR PAQR7 PEDS1-UBE2V1 PGAP2 PGLYRP3 PLN PLP1 PLP2 PLPP4 PLPP6 PMP22 PNLIPRP1 PRB1 PTCH1 RHAG RPRM RTP2 RUSF1 S100A2 SCARF1 SCGB1D1 SCRG1 SEC22A SEC22B SEC61G SELENOK SEMA6C SERP1 SFTPC SLC13A3 SLC1A1 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC35E3 SLC35G2 SLC38A7 SLC52A2 SLC7A14 SMCO4 SMIM1 SNORC STATH STX1B STX3 STX5 STX8 SYNGR1 SYT15 TECR TEX264 TFRC THBD THSD7B TM6SF2 TMBIM6 TMEM100 TMEM107 TMEM11 TMEM120A TMEM128 TMEM140 TMEM141 TMEM14B TMEM14C TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM236 TMEM243 TMEM254 TMEM42 TMEM43 TMEM47 TMEM50B TMEM60 TMEM65 TMEM72 TMEM79 TMEM86A TMEM86B TMEM97 TMPRSS4 TMUB2 TNF TNFRSF10C TNMD TRAF3IP3 TRAM1L1 TSPAN2 TSPAN33 TSPAN7 TSPO TWSG1 UBE2J1 UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1 VMP1 WFDC2 WFS1 YIPF6 ZFPL1	52 interacting genes: AARD APLP1 AQP6 BAG6 BET1 CCDC153 COPS6 CRB3 CREB3L3 EBP FAM209A GET3 GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B11 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STX8 STXBP1 TACC1 TMEM31 TP53 USO1 VAMP5 VAPB VCP VCPIP1
Entrez ID		200232	6811
HPRD ID		18536	04426
Ensembl ID		ENSG00000124103	ENSG00000162236
Uniprot IDs		Q5JX71	B4DKR0 Q13190
PDB IDs			3EFO
Enriched GO Terms of Interacting Partners?
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