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ELK1 and EWSR1
Data Source:
BioGRID
(pull down)
ELK1
EWSR1
Description
ETS transcription factor ELK1
EWS RNA binding protein 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Mitochondrion
Dendrite
Neuronal Cell Body
Axon Terminus
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Transcription Coregulator Activity
RNA Binding
Protein Binding
Calmodulin Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Response To Light Stimulus
Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Testosterone Stimulus
Cellular Response To Gamma Radiation
Response To Fibroblast Growth Factor
Positive Regulation Of Neuron Death
Regulation Of Transcription, DNA-templated
Pathways
ERK/MAPK targets
NGF-stimulated transcription
HCMV Early Events
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
Ewing's sarcoma
Myxoid liposarcoma
Clear cell sarcoma of soft tissue
Extraskeletal myxoid chondrosarcoma
GWAS
Breast cancer (
23535729
)
Pancreatic cancer (
25086665
)
Platelet count (
27863252
)
Platelet distribution width (
32888494
)
Interacting Genes
40 interacting genes:
APP
BRCA1
CDK6
CEBPB
CREBBP
CRK
EMX1
EP300
EWSR1
FBXO25
FLI1
FOS
GRB10
GRB2
HDAC1
HOXB13
ID1
ID2
ID3
KLF4
MAD2L2
MAP2K1
MAP2K3
MAPK1
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
MAPK9
MOB4
PIAS2
PLCG2
SNCA
SRF
STARD3NL
STK16
TAOK2
UBE2I
USP17L2
162 interacting genes:
ACTL6A
AGT
ANXA11
ARID1A
ATN1
ATPAF2
ATXN3
BAD
BARD1
BLZF1
BNIP3L
BRME1
BTK
C11orf16
CALM1
CCDC7
CCDC91
CD177
CDK12
CEACAM5
CETP
CFDP1
CHERP
CNST
CPSF6
CPSF7
CREBBP
CUEDC2
CXADR
DFFA
DMRTB1
DNAJB3
DYNLL2
E2F8
ECD
ELAVL3
ELAVL4
ELK1
EPAS1
ERCC5
FAM131C
FASN
FLI1
FUS
FXR2
GNPDA1
GPBP1L1
H2BC15
HBP1
HDAC3
HERPUD1
HLTF
HMGA1
HMGN4
HNRNPUL1
HSPA2
IRF3
ITCH
ITGB5
JUN
KCNMB1
KEL
KHDRBS2
KRR1
KXD1
LILRA3
MAGEA11
MAPK1IP1L
MATK
MDFI
MNS1
MRPS18B
MSC
MTCP1
MTMR9
MVK
MYL6
MYO1F
MYOZ2
NBPF3
NDRG1
NDUFB1
NDUFV1
NINL
NLE1
NONO
NPPB
NSUN4
NTNG2
PCBP1
PDHX
PEF1
PGLS
PLSCR1
POLR2G
POLR3A
POU4F1
POU5F1
PRKCA
PRMT1
PRMT8
PRR13
PRRC2A
PRTFDC1
PRUNE2
PTK2B
RAB37
RAD23A
RALYL
RASL11B
RBPMS
RFX3
RHOXF2
RMND5B
RNF183
RPL31
RPS15A
SALL2
SCMH1
SEC24A
SEC24D
SELENOI
SERP2
SF1
SF3B4
SLC1A1
SLC22A24
SMAD1
SMAD4
SMARCC1
SMARCC2
SNRPC
SSBP2
SSBP3
SUPT4H1
SUV39H2
TAF1
TFG
TMSB4Y
TONSL
TPGS2
TRAF1
TRAF2
TRAF3
TRIM37
TRIM5
TRPV5
TSPAN3
TULP2
USP7
VPS72
WBP4
WDR37
WWP1
WWP2
YWHAG
YY1AP1
ZBTB1
ZDHHC3
ZNF165
ZNF184
ZNF383
Entrez ID
2002
2130
HPRD ID
02407
00592
Ensembl ID
ENSG00000126767
ENSG00000182944
Uniprot IDs
A0A024R1A7
P19419
Q86SR6
Q01844
PDB IDs
1DUX
5VVT
2CPE
Enriched GO Terms of Interacting Partners
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