ELK1 and STARD3NL

Data Source:
BioGRID (two hybrid)

		ELK1	STARD3NL
Description		ETS transcription factor ELK1	STARD3 N-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Dendrite Neuronal Cell Body Axon Terminus	Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Cholesterol Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Testosterone Stimulus Cellular Response To Gamma Radiation Response To Fibroblast Growth Factor Positive Regulation Of Neuron Death	C21-steroid Hormone Biosynthetic Process Vesicle Tethering To Endoplasmic Reticulum
Pathways		ERK/MAPK targets NGF-stimulated transcription HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Pregnenolone biosynthesis
Drugs
Diseases
GWAS			Bone mineral density (spine) ( 19801982) Fractures ( 30158200 30598549) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 31453325 30598549 28869591) Heel bone mineral density variance ( 31453325) Height ( 20881960 25282103 25429064 31562340) Lumbar spine bone mineral density ( 22504420) Lumbar spine bone mineral density (integral) ( 27476799) Mosquito bite size ( 28199695) Rosacea symptom severity ( 29771307) Treatment response for severe sepsis ( 22310353)
Interacting Genes		40 interacting genes: APP BRCA1 CDK6 CEBPB CREBBP CRK EMX1 EP300 EWSR1 FBXO25 FLI1 FOS GRB10 GRB2 HDAC1 HOXB13 ID1 ID2 ID3 KLF4 MAD2L2 MAP2K1 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MOB4 PIAS2 PLCG2 SNCA SRF STARD3NL STK16 TAOK2 UBE2I USP17L2	3 interacting genes: CHRM5 ELK1 HCST
Entrez ID		2002	83930
HPRD ID		02407	18117
Ensembl ID		ENSG00000126767	ENSG00000010270
Uniprot IDs		A0A024R1A7 P19419 Q86SR6	A0A024RA89 O95772
PDB IDs		1DUX 5VVT
Enriched GO Terms of Interacting Partners?
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