EME2 and FANCM

Data Source:
BioGRID (pull down)

		EME2	FANCM
Description		essential meiotic structure-specific endonuclease subunit 2	FA complementation group M
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Holliday Junction Resolvase Complex	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA Binding Endonuclease Activity Protein Binding	Four-way Junction DNA Binding Chromatin Binding RNA Helicase Activity Nuclease Activity Protein Binding ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Replication Fork Processing Intra-S DNA Damage Checkpoint Nucleic Acid Phosphodiester Bond Hydrolysis	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing DNA Duplex Unwinding Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Replication Fork Reversal Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Protein Monoubiquitination
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates Fanconi Anemia Pathway	Fanconi Anemia Pathway
Drugs
Diseases			Fanconi anemia
GWAS			Metabolite levels ( 23823483) Nicotine dependence symptom count ( 25555482) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		4 interacting genes: FAAP24 FANCM MEOX2 MUS81	11 interacting genes: APP CENPX ECT2 EME2 EPN2 FAAP24 LRRK2 RMI1 RMI2 TRIM27 UBE2I
Entrez ID		197342	57697
HPRD ID		16859	13876
Ensembl ID		ENSG00000197774	ENSG00000187790
Uniprot IDs		A4GXA9	Q8IYD8
PDB IDs			4BXO 4DAY 4DRB 4E45 4M6W
Enriched GO Terms of Interacting Partners?
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