FANCM and FAAP24

Data Source:
HPRD (in vivo, two hybrid)

		FANCM	FAAP24
Description		FA complementation group M	FA core complex associated protein 24
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GO Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Nucleoplasm Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex
	Molecular Function	Four-way Junction DNA Binding Chromatin Binding RNA Helicase Activity Nuclease Activity Protein Binding ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing DNA Duplex Unwinding Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Replication Fork Reversal Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Protein Monoubiquitination	Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway	Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia
GWAS		Metabolite levels ( 23823483) Nicotine dependence symptom count ( 25555482) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		11 interacting genes: APP CENPX ECT2 EME2 EPN2 FAAP24 LRRK2 RMI1 RMI2 TRIM27 UBE2I	5 interacting genes: APP EME2 FANCM RBBP6 TERT
Entrez ID		57697	91442
HPRD ID		13876	14547
Ensembl ID		ENSG00000187790	ENSG00000131944
Uniprot IDs		Q8IYD8	A0A0S2Z5V6 K7EKQ4 Q9BTP7
PDB IDs		4BXO 4DAY 4DRB 4E45 4M6W	2LYH 2M9M 2M9N 4BXO 4M6W
Enriched GO Terms of Interacting Partners?
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