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DMPK and TK1
Data Source:
BioGRID
(two hybrid)
DMPK
TK1
Description
DM1 protein kinase
thymidine kinase 1
Image
GO Annotations
Cellular Component
Nuclear Outer Membrane
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Integral Component Of Mitochondrial Outer Membrane
Nuclear Membrane
Sarcoplasmic Reticulum Membrane
Cytosol
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Myosin Phosphatase Regulator Activity
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Thymidine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Identical Protein Binding
Biological Process
Regulation Of Sodium Ion Transport
Protein Phosphorylation
Cellular Calcium Ion Homeostasis
Nuclear Envelope Organization
Regulation Of Heart Contraction
Muscle Cell Apoptotic Process
Regulation Of Myotube Differentiation
Regulation Of Skeletal Muscle Contraction By Calcium Ion Signaling
Regulation Of Excitatory Postsynaptic Membrane Potential Involved In Skeletal Muscle Contraction
Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Regulation Of Phosphoprotein Phosphatase Activity
Regulation Of Synapse Structural Plasticity
Regulation Of Cardiac Conduction
Nucleobase-containing Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Phosphorylation
Pyrimidine Nucleoside Salvage
Thymidine Metabolic Process
Protein Homotetramerization
DNA Biosynthetic Process
Pathways
Ion homeostasis
G1/S-Specific Transcription
Pyrimidine salvage
Drugs
Bisindolylmaleimide VIII
Dithioerythritol
Thymidine 5'-triphosphate
Diseases
Myotonic dystrophy (DM)
GWAS
Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) (
30940143
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Leukocyte telomere length (
32109421
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Interacting Genes
18 interacting genes:
ANXA7
ATN1
ATXN1
CELF1
FXYD1
GABARAP
GEMIN4
HOXA2
HSPB2
PIN1
PLN
PPP1R12A
RAC1
RAF1
RPS10
SMN1
TK1
UBQLN4
162 interacting genes:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ATG16L2
ATP5F1B
ATP6V1A
ATXN3
BAG6
BOLA2
BOLA2B
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
DYNC2I1
DYNLT2B
EEF1A1
EIF3G
EIF4A2
EIF6
ERG28
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
GAPDH
GDF9
GDI1
GET3
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
INTS11
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL20-AS1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PJA1
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS1
RBBP4
RBM48
REX1BD
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPTIN6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO2
SUMO3
TAF1C
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
1760
7083
HPRD ID
05645
01771
Ensembl ID
ENSG00000104936
ENSG00000167900
Uniprot IDs
B4DM55
B4DZE2
E5KR05
E5KR06
E5KR07
I6L989
Q09013
A0A384MDV9
K7ES52
P04183
PDB IDs
1WT6
2VD5
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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