TBC1D21 and KRT37

Data Source:
BioGRID (two hybrid)

		TBC1D21	KRT37
Description		TBC1 domain family member 21	keratin 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoskeleton Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	Structural Molecule Activity Protein Binding
	Biological Process	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly	Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916)	Squamous cell lung carcinoma ( 28604730)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	41 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT3 KRT4 KRT6B KRT6C KRT71 KRT74 KRT75 KRT76 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1
Entrez ID		161514	8688
HPRD ID		15473	05175
Ensembl ID		ENSG00000167139	ENSG00000108417
Uniprot IDs		Q8IYX1	O76014
PDB IDs
Enriched GO Terms of Interacting Partners?
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