TBC1D21 and GFAP

Data Source:
BioGRID (two hybrid)

		TBC1D21	GFAP
Description		TBC1 domain family member 21	glial fibrillary acidic protein
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoskeleton Extracellular Exosome	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly	Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy
Pathways			Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	80 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 DES ENKD1 EPM2AIP1 FAM50B GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774
Entrez ID		161514	2670
HPRD ID		15473	00675
Ensembl ID		ENSG00000167139	ENSG00000131095
Uniprot IDs		Q8IYX1	A7REI1 P14136
PDB IDs			6A9P
Enriched GO Terms of Interacting Partners?
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