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KRT37 and DES
Data Source:
BioGRID
(two hybrid)
KRT37
DES
Description
keratin 37
desmin
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Intermediate Filament
Extracellular Exosome
Nucleus
Cytosol
Intermediate Filament
Fascia Adherens
Intercalated Disc
Z Disc
Neuromuscular Junction
Sarcolemma
Intermediate Filament Cytoskeleton
Extracellular Exosome
Cardiac Myofibril
Molecular Function
Structural Molecule Activity
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Cytoskeletal Protein Binding
Identical Protein Binding
Biological Process
Keratinization
Cornification
Muscle Contraction
Cytoskeleton Organization
Regulation Of Heart Contraction
Muscle Filament Sliding
Intermediate Filament Organization
Pathways
Keratinization
Formation of the cornified envelope
Striated Muscle Contraction
Drugs
Diseases
Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
Scapuloperoneal myopathy (SPM)
Dilated cardiomyopathy (DCM)
GWAS
Squamous cell lung carcinoma (
28604730
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Resting heart rate (
27798624
)
Interacting Genes
41 interacting genes:
AGXT
AQP1
BCAS2
BFSP2
C21orf58
CCDC196
CLCNKA
COL8A1
DES
FAM110A
FBXW5
GNG13
HAPLN2
HGS
HOXA1
HSF4
KRT1
KRT3
KRT4
KRT6B
KRT6C
KRT71
KRT74
KRT75
KRT76
KRT81
KRT83
KRT85
KRT86
MTG1
NUFIP2
OIP5
OTX1
PIN1
PKN1
PSMA1
SMARCD1
SMARCE1
TBC1D21
TXLNB
USHBP1
60 interacting genes:
AURKB
BAG5
BRCA1
C1orf216
CAPN1
CLIP4
CRYAB
CT55
CWF19L2
DDX6
DSP
DUX1
DUX4
EHHADH
ENO1
GFAP
GOLGA6L9
HSPB1
ITSN1
KRT13
KRT15
KRT20
KRT33B
KRT37
KRT75
LBX1
LENG1
LMO4
LONRF3
M1AP
MAPKAPK2
NEB
NEFL
NEK6
PIAS2
PIH1D2
PKD1
PLEKHA5
POLR2G
PPL
PPP1R18
PRPH
RNF4
ROCK1
S100A1
S100B
SHBG
SNAPIN
SPTAN1
SYNC
SYNM
TCEA2
TFIP11
TRIM55
TRIM63
TRIM7
UBE2I
VIM
YES1
ZMYM5
Entrez ID
8688
1674
HPRD ID
05175
00514
Ensembl ID
ENSG00000108417
ENSG00000175084
Uniprot IDs
O76014
P17661
Q53SB5
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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