TBC1D21 and SEPTIN2

Data Source:
BioGRID (two hybrid)

		TBC1D21	SEPTIN2
Description		TBC1 domain family member 21	septin 2
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoskeleton Extracellular Exosome	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	21 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 CSNK2A1 DAZAP2 ESR1 JPT2 MTOR PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5
Entrez ID		161514	4735
HPRD ID		15473	03297
Ensembl ID		ENSG00000167139	ENSG00000168385
Uniprot IDs		Q8IYX1	A0A384N6H6 Q15019
PDB IDs			2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR
Enriched GO Terms of Interacting Partners?
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