GFAP and FAM50B

Data Source:
BioGRID (two hybrid)

		GFAP	FAM50B
Description		glial fibrillary acidic protein	family with sequence similarity 50 member B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton	Nucleus Nucleoplasm Midbody Intercellular Bridge
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy	Chromatin Organization
Pathways		Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases		Alexander disease
GWAS		Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)
Interacting Genes		80 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 DES ENKD1 EPM2AIP1 FAM50B GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774	49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1
Entrez ID		2670	26240
HPRD ID		00675	16883
Ensembl ID		ENSG00000131095	ENSG00000145945
Uniprot IDs		A7REI1 P14136	A0A024QZY3 Q9Y247
PDB IDs		6A9P
Enriched GO Terms of Interacting Partners?
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