GFAP and MOS

Data Source:
BioGRID (two hybrid)

		GFAP	MOS
Description		glial fibrillary acidic protein	MOS proto-oncogene, serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton	Cytoplasm Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Signal Transduction Regulation Of Meiotic Nuclear Division Positive Regulation Of MAPK Cascade Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Pathways		Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases		Alexander disease
GWAS		Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)	Height ( 18391951) Refractive error ( 32231278)
Interacting Genes		80 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 DES ENKD1 EPM2AIP1 FAM50B GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774	56 interacting genes: ACTN2 ASB6 ATRIP BICD2 BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 DZIP1 GFAP GOLGA2 GOLGA6A GOLGA6L9 GRAP2 HOMER3 HOMEZ HSPA1A IKZF1 KCTD6 KIFAP3 KIFC3 KRT13 KRT15 KRT27 KRT31 KRT33B KRT34 KRT40 KRTAP1-3 LZTS2 MAP2K2 MEOX2 MID2 MIPOL1 MTMR9 MTUS2 MYOD1 NBPF19 NOTCH2NLA PICK1 PPP2R5A PSTPIP1 RHOU SEC24C SSX2IP TP53BP2 TRAF1 TRAF2 TRIM27 USHBP1 ZBTB2
Entrez ID		2670	4342
HPRD ID		00675	01816
Ensembl ID		ENSG00000131095	ENSG00000172680
Uniprot IDs		A7REI1 P14136	P00540
PDB IDs		6A9P
Enriched GO Terms of Interacting Partners?
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