TMEM30B and SFTPC

Data Source:
BioGRID (two hybrid)

		TMEM30B	SFTPC
Description		transmembrane protein 30B	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	Protein Binding Aminophospholipid Flippase Activity	Protein Binding Identical Protein Binding
	Biological Process	Aminophospholipid Transport Phospholipid Translocation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Aminophospholipid Translocation	Respiratory Gaseous Exchange By Respiratory System Cellular Protein Metabolic Process
Pathways			Surfactant metabolism Defective pro-SFTPC causes SMDP2 and RDS Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Nickel levels ( 26025379) Obesity-related traits ( 23251661) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		4 interacting genes: GPR42 PMP22 SCD SFTPC	36 interacting genes: BSCL2 CD200R1 CD79A CLDN5 CPLX4 CREB3 CXCL9 FAM209A FNDC9 GJA8 GOLM1 GPR152 GPX8 HPN ICAM3 IFNGR2 KLRC1 LMNA LSMEM2 MUC1 NEDD4 PDZK1IP1 PQBP1 PVR SEC22A SEC61G SIGLEC9 SMIM3 SYNE4 TMEM106C TMEM139 TMEM30B TMEM79 TMPRSS2 WWP1 WWP2
Entrez ID		161291	6440
HPRD ID		18567	01520
Ensembl ID		ENSG00000182107	ENSG00000168484
Uniprot IDs		Q3MIR4	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
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