TMEM30B and SCD

Data Source:
BioGRID (two hybrid)

		TMEM30B	SCD
Description		transmembrane protein 30B	stearoyl-CoA desaturase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Aminophospholipid Flippase Activity	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Palmitoyl-CoA 9-desaturase Activity
	Biological Process	Aminophospholipid Transport Phospholipid Translocation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Aminophospholipid Translocation	Unsaturated Fatty Acid Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Monounsaturated Fatty Acid Biosynthetic Process
Pathways			Activation of gene expression by SREBF (SREBP) Fatty acyl-CoA biosynthesis NR1H2 & NR1H3 regulate gene expression linked to lipogenesis
Drugs
Diseases
GWAS		Nickel levels ( 26025379) Obesity-related traits ( 23251661) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Glycerophospholipid levels ( 26068415) Macular thickness ( 30535121) Metabolic traits ( 21886157) Metabolite levels ( 23823483) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 23362303) Vaccenic acid (18:1n-7) levels ( 28298293) White blood cell count (basophil) ( 27863252)
Interacting Genes		4 interacting genes: GPR42 PMP22 SCD SFTPC	41 interacting genes: APP AQP6 CD207 CD33 CERS4 CLEC12B CREB3L1 CYB561 CYB5A CYBC1 ERGIC3 GJB1 GPR152 GPR42 GPX8 HSD17B13 JAGN1 KCNJ6 MARCHF5 MCFD2 MFSD14B MGST3 MTIF3 NEDD4L PVR REEP2 RETREG3 RNF5 SCN3B SEC11C SLC10A6 SLC7A14 SPAG4 STOM TIMMDC1 TLCD4 TMEM30B TMPRSS2 TMX2 UBC VMA21
Entrez ID		161291	6319
HPRD ID		18567	04941
Ensembl ID		ENSG00000182107	ENSG00000099194
Uniprot IDs		Q3MIR4	O00767
PDB IDs			4ZYO
Enriched GO Terms of Interacting Partners?
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