Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
DAB2 and PRKCG
Data Source:
HPRD
(in vitro)
DAB2
PRKCG
Description
DAB adaptor protein 2
protein kinase C gamma
Image
GO Annotations
Cellular Component
Fibrillar Center
Cytoplasm
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Clathrin-coated Vesicle
Clathrin-coated Vesicle Membrane
Intracellular Membrane-bounded Organelle
Nucleus
Cytosol
Plasma Membrane
Cell-cell Junction
Postsynaptic Density
Dendrite
Calyx Of Held
Perinuclear Region Of Cytoplasm
Synaptic Membrane
Presynaptic Cytosol
Postsynaptic Cytosol
Molecular Function
Protein Binding
Protein C-terminus Binding
Clathrin Adaptor Activity
Cargo Receptor Activity
SMAD Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Calcium-dependent Protein Kinase C Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Phosphorylation
Receptor-mediated Endocytosis
Apoptotic Process
Integrin-mediated Signaling Pathway
Multicellular Organism Development
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Protein Transport
Wnt Signaling Pathway
Positive Regulation Of Cell Migration
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Leading Edge Cell Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Endocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of Androgen Receptor Signaling Pathway
Membrane Organization
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Clathrin-dependent Endocytosis
Positive Regulation Of Early Endosome To Late Endosome Transport
Protein Phosphorylation
Chemical Synaptic Transmission
Learning Or Memory
Chemosensory Behavior
Phosphorylation
Peptidyl-serine Phosphorylation
Platelet Activation
Negative Regulation Of Protein Ubiquitination
Regulation Of Response To Food
Positive Regulation Of Mismatch Repair
Intracellular Signal Transduction
Negative Regulation Of Protein Catabolic Process
Regulation Of Circadian Rhythm
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Protein Autophosphorylation
Response To Pain
Rhythmic Process
Regulation Of Phagocytosis
Innervation
Presynaptic Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Proteasomal Protein Catabolic Process
Response To Psychosocial Stress
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Gap junction degradation
Formation of annular gap junctions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Calmodulin induced events
Disinhibition of SNARE formation
Trafficking of GluR2-containing AMPA receptors
G alpha (z) signalling events
WNT5A-dependent internalization of FZD4
Response to elevated platelet cytosolic Ca2+
Drugs
Tamoxifen
Fostamatinib
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Albumin-globulin ratio (
29403010
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Apolipoprotein A1 levels (
32203549
)
Aspartate aminotransferase levels (
29403010
)
Birth weight (
31043758
)
Chronic kidney disease (
31152163
20383146
)
Creatinine levels (
31015462
)
Diverticular disease (
30177863
)
Estimated glomerular filtration rate (
31152163
31015462
31451708
30604766
)
Estimated glomerular filtration rate in diabetes (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Glomerular filtration rate (creatinine) (
28452372
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
HDL cholesterol levels (
32203549
)
Health literacy (
31250787
)
Heel bone mineral density (
30598549
28869591
)
Height (
31562340
)
Non-albumin protein levels (
29403010
)
Pancreatic cancer (
22158540
)
Premature menopause in childhood cancer survivors (
29432556
)
Self-reported allergy (
23817569
)
Systemic lupus erythematosus (
19838195
)
Urate levels (
23263486
)
Waist-hip ratio (
28552196
)
Interacting Genes
40 interacting genes:
AP2M1
APLP1
APLP2
APP
ATXN1L
AXIN1
CDC16
CDK1
CSK
DAB2IP
DIP2A
DVL1
DVL3
FCHO1
FCHO2
FGR
GRB2
INPP5D
ITGB3
ITGB5
ITSN1
LDLR
LRP1
LRP2
LRP8
MIB1
MYO6
NECAP1
PIN1
PRKCB
PRKCD
PRKCG
SGIP1
SMAD2
SMAD3
SMURF2
SRC
SUMO2
TGFBR1
TGFBR2
64 interacting genes:
AFAP1
ANXA7
APP
ARHGEF25
ARHGEF7
CASR
CCHCR1
CD5
CDC42
CHAT
CTNNB1
CYTH2
DAB2
DDX58
DNAJC5
DVL2
EIF4E
EPHB1
EXOC5
FBXO7
GABRA1
GABRA4
GFAP
GJA1
GJA3
GRIA4
GRIN1
GRIN2B
GRIN2D
GRK2
GRM5
GSK3A
HABP4
HSPA4
IRS1
ITGB2
MAPT
MARK4
NOXA1
NRGN
NUMB
PA2G4
PARD3
PARD6A
PARD6B
PDLIM5
PEBP1
PICK1
PNMA1
PPP1R14A
RANBP10
RGS2
SCN3A
SDC2
SMURF1
STXBP1
TIAM1
TOP2A
TRIM5
UBE2T
VTN
YWHAB
YWHAE
YWHAG
Entrez ID
1601
5582
HPRD ID
03139
01502
Ensembl ID
ENSG00000153071
ENSG00000126583
Uniprot IDs
A0A024R036
B2RAW0
P98082
B2R5T1
B7Z3W6
P05129
PDB IDs
2LSW
6O5O
6OVF
2E73
2UZP
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?