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PRKCG and UBE2T
Data Source:
BioGRID
(enzymatic study)
PRKCG
UBE2T
Description
protein kinase C gamma
ubiquitin conjugating enzyme E2 T
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Plasma Membrane
Cell-cell Junction
Postsynaptic Density
Dendrite
Calyx Of Held
Perinuclear Region Of Cytoplasm
Synaptic Membrane
Presynaptic Cytosol
Postsynaptic Cytosol
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Calcium-dependent Protein Kinase C Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Phosphorylation
Chemical Synaptic Transmission
Learning Or Memory
Chemosensory Behavior
Phosphorylation
Peptidyl-serine Phosphorylation
Platelet Activation
Negative Regulation Of Protein Ubiquitination
Regulation Of Response To Food
Positive Regulation Of Mismatch Repair
Intracellular Signal Transduction
Negative Regulation Of Protein Catabolic Process
Regulation Of Circadian Rhythm
Response To Morphine
Negative Regulation Of Neuron Apoptotic Process
Protein Autophosphorylation
Response To Pain
Rhythmic Process
Regulation Of Phagocytosis
Innervation
Presynaptic Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Proteasomal Protein Catabolic Process
Response To Psychosocial Stress
Regulation Of Synaptic Vesicle Exocytosis
Protein Polyubiquitination
DNA Repair
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Protein Ubiquitination
Protein K29-linked Ubiquitination
Interstrand Cross-link Repair
Protein K27-linked Ubiquitination
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Calmodulin induced events
Disinhibition of SNARE formation
Trafficking of GluR2-containing AMPA receptors
G alpha (z) signalling events
WNT5A-dependent internalization of FZD4
Response to elevated platelet cytosolic Ca2+
Fanconi Anemia Pathway
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Tamoxifen
Fostamatinib
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Breast cancer (
23535733
)
Celiac disease (
23936387
)
Interacting Genes
64 interacting genes:
AFAP1
ANXA7
APP
ARHGEF25
ARHGEF7
CASR
CCHCR1
CD5
CDC42
CHAT
CTNNB1
CYTH2
DAB2
DDX58
DNAJC5
DVL2
EIF4E
EPHB1
EXOC5
FBXO7
GABRA1
GABRA4
GFAP
GJA1
GJA3
GRIA4
GRIN1
GRIN2B
GRIN2D
GRK2
GRM5
GSK3A
HABP4
HSPA4
IRS1
ITGB2
MAPT
MARK4
NOXA1
NRGN
NUMB
PA2G4
PARD3
PARD6A
PARD6B
PDLIM5
PEBP1
PICK1
PNMA1
PPP1R14A
RANBP10
RGS2
SCN3A
SDC2
SMURF1
STXBP1
TIAM1
TOP2A
TRIM5
UBE2T
VTN
YWHAB
YWHAE
YWHAG
22 interacting genes:
AMFR
ARIH2
BRCA1
CDK2
CHEK1
FANCD2
FANCL
LNX2
MARCHF5
MGRN1
PCGF2
PRKCG
PRKN
RNF128
RNF144B
RNF31
RNF4
ROCK1
RPS6KA1
TRIM27
UBA1
UBA6
Entrez ID
5582
29089
HPRD ID
01502
13704
Ensembl ID
ENSG00000126583
ENSG00000077152
Uniprot IDs
B2R5T1
B7Z3W6
P05129
A0A024R9A9
Q9NPD8
PDB IDs
2E73
2UZP
1YH2
4CCG
5NGZ
5OJJ
6R75
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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