DAB2 and INPP5D

DAB2

INPP5D

Description DAB adaptor protein 2 inositol polyphosphate-5-phosphatase D
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Alzheimer's disease (late onset) ( 30617256 24162737)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Contrast sensitivity ( 24152035)
  • Crohn's disease ( 22412388 23128233)
  • Eosinophil counts ( 32888494 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Family history of Alzheimer's disease ( 30617256)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Neutrophil count ( 32888494)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Perceived unattractiveness to mosquitoes ( 28199695)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 40 interacting genes: AP2M1 APLP1 APLP2 APP ATXN1L AXIN1 CDC16 CDK1 CSK DAB2IP DIP2A DVL1 DVL3 FCHO1 FCHO2 FGR GRB2 INPP5D ITGB3 ITGB5 ITSN1 LDLR LRP1 LRP2 LRP8 MIB1 MYO6 NECAP1 PIN1 PRKCB PRKCD PRKCG SGIP1 SMAD2 SMAD3 SMURF2 SRC SUMO2 TGFBR1 TGFBR2 45 interacting genes: ARAP1 CD22 CD300LF CRKL CSF1R CSF3R CYSRT1 DAB1 DAB2 DOK1 DOK2 DOK3 EPOR FCGR1B FCGR2B FGR FLT3 GAB1 GAB2 GRB2 HCK IL4R JAK1 JAK3 KHDRBS3 KIT KRT31 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP6-3 LILRB4 LYN MET NOTCH2NLA PECAM1 PLCG1 PTPN11 SH3KBP1 SHC1 SLAMF1 XIAP ZDHHC17
Entrez ID 1601 3635
HPRD ID 03139 09033
Ensembl ID ENSG00000153071 ENSG00000168918
Uniprot IDs A0A024R036 B2RAW0 P98082 Q92835
PDB IDs 2LSW 6O5O 6OVF 2YSX 6IBD 6XY7
Enriched GO Terms of Interacting Partners?
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