PRAG1 and CHGB

Data Source:
BioGRID (two hybrid)

		PRAG1	CHGB
Description		PEAK1 related, kinase-activating pseudokinase 1	chromogranin B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Focal Adhesion	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Identical Protein Binding	Hormone Activity Protein Binding
	Biological Process	Protein Phosphorylation Regulation Of Cell Shape Regulation Of Notch Signaling Pathway Negative Regulation Of Neuron Projection Development Cell Migration Positive Regulation Of Rho Protein Signal Transduction Regulation Of Cell Motility	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) Processed meat consumption ( 32066663) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Thyroid stimulating hormone levels ( 32769997) TPE interval (resting) ( 32386560)	Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		3 interacting genes: CHGB PSAP UBE3A	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		157285	1114
HPRD ID		19497	07512
Ensembl ID		ENSG00000275342	ENSG00000089199
Uniprot IDs		Q86YV5	P05060
PDB IDs		5VE6
Enriched GO Terms of Interacting Partners?
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