CHGB and TWF2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHGB	TWF2
Description		chromogranin B	twinfilin actin binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule	Cytoplasm Actin Filament Myofibril Lamellipodium Filopodium Growth Cone Stereocilium Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding	RNA Binding Actin Monomer Binding Protein Kinase C Binding Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Cadherin Binding Actin Filament Binding
	Biological Process	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process	Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Cell Projection Organization Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Microvillus Length Regulation Of Actin Cytoskeleton Organization Sequestering Of Actin Monomers Positive Regulation Of Axon Extension Barbed-end Actin Filament Capping Cellular Response To Retinoic Acid Cellular Response To Growth Factor Stimulus
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Schizophrenia ( 23974872)
Interacting Genes		34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	6 interacting genes: ARHGDIA CHGB FOXJ1 ILK POT1 TERF2IP
Entrez ID		1114	11344
HPRD ID		07512	08464
Ensembl ID		ENSG00000089199	ENSG00000247596
Uniprot IDs		P05060	Q6IBS0
PDB IDs			2VAC 2W0I
Enriched GO Terms of Interacting Partners?
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