CHGB and SLC25A6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHGB	SLC25A6
Description		chromogranin B	solute carrier family 25 member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule	Nucleus Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane Integral Component Of Membrane
	Molecular Function	Hormone Activity Protein Binding	ATP:ADP Antiporter Activity Protein Binding
	Biological Process	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Targeting To Mitochondrion Apoptotic Process Viral Process Regulation Of Insulin Secretion Mitochondrial ADP Transmembrane Transport Mitochondrial ATP Transmembrane Transport
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			Clodronic acid Etidronic acid
Diseases
GWAS		Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	20 interacting genes: AP2B1 CHEK2 CHGB DUX4 FGFR3 KARS1 KRT31 KRTAP4-12 LZTS2 MID2 MTUS2 NOTCH2NLA PLSCR1 PRSS23 STRN4 TEKT4 TRAF1 TRIM23 TRIP6 VIM
Entrez ID		1114	293
HPRD ID		07512	02461
Ensembl ID		ENSG00000089199	ENSG00000169100
Uniprot IDs		P05060	P12236 Q6I9V5
PDB IDs
Enriched GO Terms of Interacting Partners?
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