CHGB and MOGS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHGB	MOGS
Description		chromogranin B	mannosyl-oligosaccharide glucosidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity
	Biological Process	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	1 interacting genes: CHGB
Entrez ID		1114	7841
HPRD ID		07512	03214
Ensembl ID		ENSG00000089199	ENSG00000115275
Uniprot IDs		P05060	A0A384MDR6 Q13724 Q58F09
PDB IDs
Enriched GO Terms of Interacting Partners?
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