CSTA and LORICRIN

		CSTA	LORICRIN
Description		cystatin A	loricrin cornified envelope precursor protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleoplasm Cytoplasm Cytosol	Cornified Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protease Binding Cysteine-type Endopeptidase Inhibitor Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Keratinocyte Differentiation Negative Regulation Of Proteolysis Cornification Cell-cell Adhesion	Cytoskeleton Organization Peptide Cross-linking Keratinocyte Differentiation Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases			Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS		Apolipoprotein B levels ( 32203549) Calcium levels ( 25972035 29403010 20705733)
Interacting Genes		12 interacting genes: CTSB CTSH CTSL DSP EVPL IVL KRT1 LORICRIN PI3 PTN UCHL5 ZDHHC17	7 interacting genes: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM
Entrez ID		1475	4014
HPRD ID		01697	01070
Ensembl ID		ENSG00000121552	ENSG00000203782
Uniprot IDs		P01040	P23490
PDB IDs		1CYU 1CYV 1DVC 1DVD 1GD3 1GD4 1N9J 1NB3 1NB5 3K9M 3KFQ 3KSE
Enriched GO Terms of Interacting Partners?
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