LORICRIN and EVPL

Data Source:
HPRD (in vivo)

		LORICRIN	EVPL
Description		loricrin cornified envelope precursor protein	envoplakin
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytoplasm Cytosol	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding
	Biological Process	Cytoskeleton Organization Peptide Cross-linking Keratinocyte Differentiation Cornification	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases		Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS			Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		7 interacting genes: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM	14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3
Entrez ID		4014	2125
HPRD ID		01070	03352
Ensembl ID		ENSG00000203782	ENSG00000167880
Uniprot IDs		P23490	B7ZLH8 K7EKI0 Q92817
PDB IDs			4QMD
Enriched GO Terms of Interacting Partners?
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