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CSNK2B and TRIM54
Data Source:
BioGRID
(two hybrid)
CSNK2B
TRIM54
Description
casein kinase 2 beta
tripartite motif containing 54
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Protein Kinase CK2 Complex
PcG Protein Complex
Secretory Granule Lumen
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Cytoplasm
Microtubule
Microtubule Associated Complex
Z Disc
Molecular Function
Chromatin Binding
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Regulator Activity
Protein Domain Specific Binding
Identical Protein Binding
Metal Ion Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Folding
Phosphatidylcholine Biosynthetic Process
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Wnt Signaling Pathway
Macroautophagy
Peptidyl-threonine Phosphorylation
Positive Regulation Of Activin Receptor Signaling Pathway
Adiponectin-activated Signaling Pathway
Cellular Protein-containing Complex Assembly
Neutrophil Degranulation
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Protein Kinase Activity
Regulation Of DNA Binding
Endothelial Tube Morphogenesis
Regulation Of Signal Transduction By P53 Class Mediator
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organism Development
Protein Ubiquitination
Cell Differentiation
Pathways
Synthesis of PC
WNT mediated activation of DVL
Condensation of Prometaphase Chromosomes
Signal transduction by L1
Neutrophil degranulation
Regulation of TP53 Activity through Phosphorylation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Receptor Mediated Mitophagy
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN stability and activity
Drugs
ATP
Quercetin
Diseases
GWAS
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Cutaneous lupus erythematosus (
25827949
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Systemic lupus erythematosus (
26316170
)
Ulcerative colitis (
28067908
)
Mean corpuscular hemoglobin (
32888494
)
Interacting Genes
223 interacting genes:
ABHD4
ACTB
ACTL6B
ACTR1B
ACTR5
ACVRL1
ADD1
ADH5
ANGPT2
ANKRD28
AP2M1
APLP1
ARAF
ATF1
ATG101
ATXN3
BAG6
BANP
BCCIP
BHLHE41
BID
BMI1
BRCA1
BTF3
C6orf136
CACNA1A
CALM1
CBX4
CCDC115
CCDC187
CCNH
CD163
CD81
CDC25B
CDC34
CDK1
CDK20
CDKN1A
CENPB
CHEK1
CHRNA4
CIC
CIPC
CLOCK
COIL
COL4A2
COPS3
COPS7A
CPNE7
CSN1S1
CSN2
CSNK1E
CSNK2A1
CSNK2A2
CST1
CTDP1
CTNNB1
DACT1
DALRD3
DELEC1
DENND5A
DNMT1
DPF3
DUX1
DYNLT2B
EIF2S2
EIF5
EIF6
EPS8
ERCC6
ERCC8
ESR1
FAF1
FAM86C1P
FBXL15
FBXL5
FGB
FGF1
FGF2
FIBP
FKBP3
FTH1
GADD45GIP1
GAMT
GBP2
GLB1
GLIS2
GNB5
GRK2
GSK3B
HEXB
HIRIP3
HNRNPA2B1
HOXB5
HOXB6
HTRA1
HYPK
IER3IP1
INO80B
INTS11
IRS1
ITSN1
KDM6B
KIF2C
LCK
LEPR
LMO4
LRP5L
LTB4R2
LYN
LYST
MAPK14
MBD4
MDM2
MME
MOXD1
MPP2
NAP1L1
NCF1
NGDN
NMT2
NOLC1
NOTCH3
NPAS2
NRBP1
NRF1
NTAQ1
ODC1
OGA
OGT
PDS5A
PER1
PER2
PFKFB4
PHC2
PHF11
PHRF1
PIMREG
PIN1
PITPNA
PLXNA3
POT1
PPID
PPP1CA
PPP1CB
PPP1CC
PPP2CA
PPP2R1A
PPP2R1B
PPP2R5D
PPP2R5E
PPP3CC
PRKAB2
PRKCZ
PRNP
PROC
PTPRK
PTTG2
PYROXD2
RAD51
RBM39
RFC1
RNF126
RNF7
RORB
RPA1
RPL13
RPL41
RPL5
RPS6KA5
RPS6KB1
RPS6KB2
RRAD
RXRA
SARNP
SDHA
SEC11A
SELENOI
SHANK3
SHMT1
SHMT2
SIMC1
SIRT1
SNX2
SPOUT1
SPSB3
SSB
STAT5A
STAU1
STK16
SUMO2
SYNE4
TCEAL7
TENM1
TFAP2A
TFAP2D
TLE1
TLX3
TNFAIP1
TOP2B
TP53
TP53BP2
TP63
TRIM54
TSEN54
TUBB2B
TWF1
UBE2I
UPF1
USO1
UTP14A
VDAC1
VRK3
WDR1
WDR18
WFIKKN1
WWOX
ZNF19
ZNF410
ZNF44
ZNF71
ZNF784
ZNHIT1
317 interacting genes:
AAMDC
ABHD17C
ADCY4
AGFG1
AIFM2
AK2
AK3
ANKRD11
ANKRD45
ARFIP2
ARHGAP29
ARHGEF5
ARHGEF6
ARMC7
ATXN3
ATXN3L
ATXN7
BBX
BMF
BSCL2
BYSL
C14orf39
C1orf109
C1orf216
C1orf35
C1QTNF2
C2CD6
C2orf49
C8orf74
CALM3
CARD9
CAVIN2
CBX8
CCDC102B
CCDC146
CCDC17
CCDC26
CCDC28A
CCDC87
CCHCR1
CCNC
CDC37
CDK18
CDKAL1
CDKN1A
CENPX
CEP57L1
CEP68
CFAP100
CFAP206
CFAP53
CHCHD2
CHD2
CHD3
CKM
CLPP
CMIP
CNGA3
CRADD
CSNK2B
CTNNA3
CWF19L2
CYTH4
DAXX
DCAF8
DCLRE1B
DCUN1D1
DDX6
DEUP1
DNAL4
DNASE1L1
DPYSL4
DRG2
DTNB
DTX2
DUSP16
DVL3
DYNC2I2
DYNLL1
EHHADH
EIF4E2
ELMO1
ELOA
ENKD1
EPHB2
EPM2AIP1
EXOC7
EXOC8
EXOSC5
EXTL2
FAM110A
FAM124A
FAM124B
FAM161A
FAM50B
FAM90A1
FAM9A
FARS2
FBF1
FBXO16
FBXW2
FLNC
FMNL1
G2E3
GAS8
GEM
GIMAP2
GLP2R
GMCL1
GNG13
GNL3L
GTF2I
GTF2IRD2
GTF2IRD2B
HAUS1
HBG1
HDAC10
HGS
HMMR
HOXB5
HSF2
HSPB1
HYAL2
IL18RAP
IL36A
IL4I1
ING3
INPP5J
IQUB
ITGAE
ITPKB
JOSD1
KANK2
KAT14
KDM1A
KIF9
KIFC3
KLHL38
KLHL42
KPNA2
KRT1
KRT3
KRT4
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRT78
KRT79
KRT8
KRTAP11-1
KRTAP9-2
LENG1
LIN37
LINC00887
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAD2L2
MAOB
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MGARP
MICAL2
MID2
MNS1
MRTFA
MSH5
MYLK2
MYO15B
MYO5B
NEK6
NGLY1
NTAQ1
NUP54
NUP58
OFCC1
OSGIN1
OSTF1
OTUB1
OTUB2
PABPC3
PAIP2
PARVG
PCDHGB1
PCDHGC3
PCSK7
PDZK1IP1
PICK1
PIK3R3
PIWIL1
PLEKHM1
PLK4
PPIG
PPP1R18
PRF1
PRKAB2
PRKG1
PRMT5
PRPF18
PRR35
PSMA1
PYGM
RAB35
RABGEF1
RAD23A
RAPSN
RASSF10
RBM15B
RBM41
RCOR3
RELT
RIMS3
RNF4
RSRC2
RUNX1T1
SCNM1
SDCBP
SEC14L4
SELE
SEMA4C
SENP3
SH2D1B
SHC3
SLC13A2
SLITRK3
SMARCD1
SMARCE1
SNF8
SOX14
SPG21
SPRING1
SSX2IP
STAM
STRC
STXBP4
STYXL1
SYCE3
SYTL5
TBC1D22B
TCAF1
TCAP
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP4
THOC1
TJAP1
TLE6
TLR10
TMEM30A
TNFAIP1
TNR
TRIM55
TRIM63
TRIM69
TRIML2
TSG101
TSHZ3
TSPEAR
TSSK3
TTC23
TTC9C
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2N
UBE2U
UBE2V2
UBL4A
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP35
USP4
USP5
USP7
USP8
UTP14C
VAMP4
VCAM1
VCP
VPS28
VPS9D1
XAF1
YEATS4
YOD1
ZBTB16
ZFHX3
ZGPAT
ZNF180
ZNF182
ZNF250
ZNF267
ZNF366
ZNF417
ZNF572
ZNF587
ZNF667-AS1
Entrez ID
1460
57159
HPRD ID
00278
05928
Ensembl ID
ENSG00000204435
ENSG00000138100
Uniprot IDs
A0A1U9X7J2
N0E4C7
P67870
Q9BYV2
PDB IDs
1DS5
1JWH
1QF8
3EED
4DGL
4MD7
4MD8
4MD9
4NH1
6Q38
3Q1D
Enriched GO Terms of Interacting Partners
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