CSNK2B and RPL41

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		CSNK2B	RPL41
Description		casein kinase 2 beta	ribosomal protein L41
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Protein Kinase CK2 Complex PcG Protein Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Endoplasmic Reticulum Cytosol Cytosolic Large Ribosomal Subunit Polysomal Ribosome
	Molecular Function	Chromatin Binding Protein Serine/threonine Kinase Activity Signaling Receptor Binding Protein Binding Transcription Factor Binding Protein Kinase Regulator Activity Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding
	Biological Process	Protein Folding Phosphatidylcholine Biosynthetic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Wnt Signaling Pathway Macroautophagy Peptidyl-threonine Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Cellular Protein-containing Complex Assembly Neutrophil Degranulation Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Kinase Activity Regulation Of DNA Binding Endothelial Tube Morphogenesis Regulation Of Signal Transduction By P53 Class Mediator	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Synthesis of PC WNT mediated activation of DVL Condensation of Prometaphase Chromosomes Signal transduction by L1 Neutrophil degranulation Regulation of TP53 Activity through Phosphorylation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Receptor Mediated Mitophagy RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN stability and activity	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		ATP Quercetin
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Systemic lupus erythematosus ( 26316170) Ulcerative colitis ( 28067908)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic sclerosis ( 21779181)
Interacting Genes		223 interacting genes: ABHD4 ACTB ACTL6B ACTR1B ACTR5 ACVRL1 ADD1 ADH5 ANGPT2 ANKRD28 AP2M1 APLP1 ARAF ATF1 ATG101 ATXN3 BAG6 BANP BCCIP BHLHE41 BID BMI1 BRCA1 BTF3 C6orf136 CACNA1A CALM1 CBX4 CCDC115 CCDC187 CCNH CD163 CD81 CDC25B CDC34 CDK1 CDK20 CDKN1A CENPB CHEK1 CHRNA4 CIC CIPC CLOCK COIL COL4A2 COPS3 COPS7A CPNE7 CSN1S1 CSN2 CSNK1E CSNK2A1 CSNK2A2 CST1 CTDP1 CTNNB1 DACT1 DALRD3 DELEC1 DENND5A DNMT1 DPF3 DUX1 DYNLT2B EIF2S2 EIF5 EIF6 EPS8 ERCC6 ERCC8 ESR1 FAF1 FAM86C1P FBXL15 FBXL5 FGB FGF1 FGF2 FIBP FKBP3 FTH1 GADD45GIP1 GAMT GBP2 GLB1 GLIS2 GNB5 GRK2 GSK3B HEXB HIRIP3 HNRNPA2B1 HOXB5 HOXB6 HTRA1 HYPK IER3IP1 INO80B INTS11 IRS1 ITSN1 KDM6B KIF2C LCK LEPR LMO4 LRP5L LTB4R2 LYN LYST MAPK14 MBD4 MDM2 MME MOXD1 MPP2 NAP1L1 NCF1 NGDN NMT2 NOLC1 NOTCH3 NPAS2 NRBP1 NRF1 NTAQ1 ODC1 OGA OGT PDS5A PER1 PER2 PFKFB4 PHC2 PHF11 PHRF1 PIMREG PIN1 PITPNA PLXNA3 POT1 PPID PPP1CA PPP1CB PPP1CC PPP2CA PPP2R1A PPP2R1B PPP2R5D PPP2R5E PPP3CC PRKAB2 PRKCZ PRNP PROC PTPRK PTTG2 PYROXD2 RAD51 RBM39 RFC1 RNF126 RNF7 RORB RPA1 RPL13 RPL41 RPL5 RPS6KA5 RPS6KB1 RPS6KB2 RRAD RXRA SARNP SDHA SEC11A SELENOI SHANK3 SHMT1 SHMT2 SIMC1 SIRT1 SNX2 SPOUT1 SPSB3 SSB STAT5A STAU1 STK16 SUMO2 SYNE4 TCEAL7 TENM1 TFAP2A TFAP2D TLE1 TLX3 TNFAIP1 TOP2B TP53 TP53BP2 TP63 TRIM54 TSEN54 TUBB2B TWF1 UBE2I UPF1 USO1 UTP14A VDAC1 VRK3 WDR1 WDR18 WFIKKN1 WWOX ZNF19 ZNF410 ZNF44 ZNF71 ZNF784 ZNHIT1	9 interacting genes: APP CSNK2B DAPK1 IKBKG MAPK14 NUPR1 PRNP SDCBP2 SRPK2
Entrez ID		1460	6171
HPRD ID		00278	17999
Ensembl ID		ENSG00000204435	ENSG00000229117
Uniprot IDs		A0A1U9X7J2 N0E4C7 P67870	A0A024RB15 P62945
PDB IDs		1DS5 1JWH 1QF8 3EED 4DGL 4MD7 4MD8 4MD9 4NH1 6Q38	4UG0 4V6X 5A2Q 5AJ0 5LKS 5OA3 5VYC 6EK0 6G5H 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMW 6ZOJ 6ZOK 6ZON 6ZP4 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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