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CLDN7 and LAT
Data Source:
BioGRID
(two hybrid)
CLDN7
LAT
Description
claudin 7
linker for activation of T cells
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Immunological Synapse
Golgi Apparatus
Plasma Membrane
COP9 Signalosome
Integral Component Of Membrane
Membrane Raft
Molecular Function
Structural Molecule Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Cell Adhesion Molecule Binding
Protein Binding
Protein Kinase Binding
Signaling Receptor Complex Adaptor Activity
Biological Process
Cell Adhesion
Negative Regulation Of Cell Adhesion
Positive Regulation Of Cell Population Proliferation
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Apoptotic Process
Response To Ethanol
Bicellular Tight Junction Assembly
Positive Regulation Of Cell Motility
MAPK Cascade
Adaptive Immune Response
Inflammatory Response
Immune Response
Integrin-mediated Signaling Pathway
Ras Protein Signal Transduction
Calcium-mediated Signaling
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
T Cell Activation
Mast Cell Degranulation
Positive Regulation Of Protein Kinase Activity
T Cell Receptor Signaling Pathway
Regulation Of T Cell Activation
Pathways
Tight junction interactions
GPVI-mediated activation cascade
Generation of second messenger molecules
Drugs
Diseases
GWAS
Birth weight (
31043758
27680694
)
FEV1 (
30804560
)
Lung function (FVC) (
30804560
)
Multiple sclerosis (
31604244
)
Offspring birth weight (
31043758
)
Allergic disease (asthma, hay fever or eczema) (
29679657
)
Crohn's disease (
21102463
)
Educational attainment (
25201988
)
Interacting Genes
77 interacting genes:
AIG1
ANKRD46
APOD
AQP2
ASGR1
BCL2L2
BET1
BMP10
C3orf52
CD53
CD72
CLN6
CMTM5
CNIH1
COL4A5
CXCL16
CXCL9
CYB561A3
CYB561D2
CYB5B
CYBC1
EDDM3B
EMP3
EPCAM
ERG28
ERMP1
FAXDC2
FXYD6
GIMAP5
GLP1R
GPR37L1
HGD
IGFBP5
ITM2A
JAGN1
LAT
LEPROTL1
LPAR3
LSMEM2
MAL
MALL
MFSD5
MS4A13
NDUFB11
NIPAL4
NKG7
OLFM4
PGAP2
PLN
RHOXF2
RPRM
RTP2
SCAMP4
SCARF1
SEC22B
SERTM1
SLC38A7
SYNE4
TJP1
TMEM100
TMEM11
TMEM128
TMEM140
TMEM147
TMEM44
TMEM60
TMEM97
TNF
TRARG1
TSPAN33
UBIAD1
UNC93B1
UPK1B
UPK2
VAMP3
VAMP5
VSTM1
95 interacting genes:
APH1A
ASGR2
BCL2L13
BSCL2
CAMLG
CBL
CD244
CD3G
CD4
CD53
CD8A
CDIP1
CLDN2
CLDN5
CLDN7
CREB3
CXorf66
CYBC1
EGFR
FCGR1A
FCGR2A
FFAR2
FFAR3
FKBP7
FYN
GAB2
GJA8
GJB1
GJB3
GOLM1
GPR101
GPR151
GPR152
GPR42
GRAP
GRAP2
GRB2
ITK
JSRP1
KASH5
KCTD17
KIR2DL3
LCK
LCP2
LEUTX
LHFPL1
LHFPL5
LMNA
MAP1LC3C
MAP4K1
MEOX2
MFF
MFSD14B
MFSD5
MRPS18B
MS4A7
MTIF3
NDUFAF2
OPRM1
PIK3R1
PLCG1
PLCG2
PRR4
PSCA
PTPN1
PTPN6
PTPRJ
SAR1A
SERINC2
SGTA
SGTB
SH3BP2
SHB
SLA
SLC14A2
SLC16A2
SLC18A1
SLC19A3
SLC26A6
SLC35C2
SLC51B
SLPI
SSMEM1
SYK
SYT2
THAP4
TM4SF18
TMEM237
TMEM45B
TMEM80
TNFRSF10D
VAV1
ZAP70
ZDHHC7
ZHX2
Entrez ID
1366
27040
HPRD ID
07633
03832
Ensembl ID
ENSG00000181885
ENSG00000213658
Uniprot IDs
A0A384ME58
F5H496
O95471
A0A024QZD6
O43561
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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