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CLDN7 and BMP10
Data Source:
BioGRID
(two hybrid)
CLDN7
BMP10
Description
claudin 7
bone morphogenetic protein 10
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Extracellular Region
Extracellular Space
Cytoplasm
Cell Surface
Z Disc
Molecular Function
Structural Molecule Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Cell Adhesion Molecule Binding
Cytokine Activity
Hormone Activity
Protein Binding
Growth Factor Activity
Telethonin Binding
Receptor Serine/threonine Kinase Binding
Biological Process
Cell Adhesion
Negative Regulation Of Cell Adhesion
Positive Regulation Of Cell Population Proliferation
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Apoptotic Process
Response To Ethanol
Bicellular Tight Junction Assembly
Positive Regulation Of Cell Motility
Kidney Development
Cell Adhesion
Adult Heart Development
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
Negative Regulation Of Cell Migration
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Sarcomere Organization
Positive Regulation Of Transcription, DNA-templated
Atrial Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Cell Development
Regulation Of Cardiac Muscle Contraction
Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Sarcomere Organization
Heart Trabecula Formation
Pathway-restricted SMAD Protein Phosphorylation
SMAD Protein Signal Transduction
Positive Regulation Of Cartilage Development
Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Tight junction interactions
Signaling by BMP
Molecules associated with elastic fibres
Drugs
Diseases
GWAS
Birth weight (
31043758
27680694
)
FEV1 (
30804560
)
Lung function (FVC) (
30804560
)
Multiple sclerosis (
31604244
)
Offspring birth weight (
31043758
)
Interacting Genes
77 interacting genes:
AIG1
ANKRD46
APOD
AQP2
ASGR1
BCL2L2
BET1
BMP10
C3orf52
CD53
CD72
CLN6
CMTM5
CNIH1
COL4A5
CXCL16
CXCL9
CYB561A3
CYB561D2
CYB5B
CYBC1
EDDM3B
EMP3
EPCAM
ERG28
ERMP1
FAXDC2
FXYD6
GIMAP5
GLP1R
GPR37L1
HGD
IGFBP5
ITM2A
JAGN1
LAT
LEPROTL1
LPAR3
LSMEM2
MAL
MALL
MFSD5
MS4A13
NDUFB11
NIPAL4
NKG7
OLFM4
PGAP2
PLN
RHOXF2
RPRM
RTP2
SCAMP4
SCARF1
SEC22B
SERTM1
SLC38A7
SYNE4
TJP1
TMEM100
TMEM11
TMEM128
TMEM140
TMEM147
TMEM44
TMEM60
TMEM97
TNF
TRARG1
TSPAN33
UBIAD1
UNC93B1
UPK1B
UPK2
VAMP3
VAMP5
VSTM1
59 interacting genes:
ACVR2A
ACVR2B
APOA5
AQP6
ARL13B
BIK
BMPR2
BSCL2
BSND
CCDC70
CD33
CISD2
CLDN7
COQ9
CREB3L1
DEXI
EBP
ERP29
FAM209A
FCGR1A
FCRL4
FFAR2
FKBP7
FNDC9
GGT6
GJB1
GPR152
GPX8
IL3RA
JAGN1
KIR2DL3
KIR3DL1
KLRC1
LRRC25
LRRC4C
MGST3
MRPS18B
MS4A3
MTIF3
PLPP4
REEP4
SERINC3
SIT1
SLC10A1
SLC10A6
SLC35C2
SLC38A1
SLC4A1
SPAG4
TCTA
TMEM14B
TMEM31
TMEM45B
TMEM86B
TMPRSS2
TNFSF14
TNFSF8
TSPAN31
VSIR
Entrez ID
1366
27302
HPRD ID
07633
09788
Ensembl ID
ENSG00000181885
ENSG00000163217
Uniprot IDs
A0A384ME58
F5H496
O95471
O95393
PDB IDs
6SF1
6SF3
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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