LAT and ZDHHC7

Data Source:
BioGRID (two hybrid)

		LAT	ZDHHC7
Description		linker for activation of T cells	zinc finger DHHC-type palmitoyltransferase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Golgi Apparatus Plasma Membrane COP9 Signalosome Integral Component Of Membrane Membrane Raft	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Signaling Receptor Complex Adaptor Activity	Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	MAPK Cascade Adaptive Immune Response Inflammatory Response Immune Response Integrin-mediated Signaling Pathway Ras Protein Signal Transduction Calcium-mediated Signaling Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway T Cell Activation Mast Cell Degranulation Positive Regulation Of Protein Kinase Activity T Cell Receptor Signaling Pathway Regulation Of T Cell Activation	Protein Targeting To Membrane Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Catabolic Process Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Polarized Epithelial Cell Differentiation Glucose Import In Response To Insulin Stimulus Regulation Of Protein Localization To Cell-cell Junction Regulation Of Fas Signaling Pathway Regulation Of Protein Localization To Plasma Membrane
Pathways		GPVI-mediated activation cascade Generation of second messenger molecules	Extra-nuclear estrogen signaling
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Crohn's disease ( 21102463) Educational attainment ( 25201988)	Height ( 25282103 18391951) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
Interacting Genes		95 interacting genes: APH1A ASGR2 BCL2L13 BSCL2 CAMLG CBL CD244 CD3G CD4 CD53 CD8A CDIP1 CLDN2 CLDN5 CLDN7 CREB3 CXorf66 CYBC1 EGFR FCGR1A FCGR2A FFAR2 FFAR3 FKBP7 FYN GAB2 GJA8 GJB1 GJB3 GOLM1 GPR101 GPR151 GPR152 GPR42 GRAP GRAP2 GRB2 ITK JSRP1 KASH5 KCTD17 KIR2DL3 LCK LCP2 LEUTX LHFPL1 LHFPL5 LMNA MAP1LC3C MAP4K1 MEOX2 MFF MFSD14B MFSD5 MRPS18B MS4A7 MTIF3 NDUFAF2 OPRM1 PIK3R1 PLCG1 PLCG2 PRR4 PSCA PTPN1 PTPN6 PTPRJ SAR1A SERINC2 SGTA SGTB SH3BP2 SHB SLA SLC14A2 SLC16A2 SLC18A1 SLC19A3 SLC26A6 SLC35C2 SLC51B SLPI SSMEM1 SYK SYT2 THAP4 TM4SF18 TMEM237 TMEM45B TMEM80 TNFRSF10D VAV1 ZAP70 ZDHHC7 ZHX2	5 interacting genes: APP CYB561 LAT PBX2 YIPF1
Entrez ID		27040	55625
HPRD ID		03832	15722
Ensembl ID		ENSG00000213658	ENSG00000153786
Uniprot IDs		A0A024QZD6 O43561	Q9NXF8
PDB IDs
Enriched GO Terms of Interacting Partners?
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