CLDN7 and UBIAD1

Data Source:
BioGRID (two hybrid)

		CLDN7	UBIAD1
Description		claudin 7	UbiA prenyltransferase domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Golgi Membrane Mitochondrial Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding	Prenyltransferase Activity Protein Binding Antioxidant Activity
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Population Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Bicellular Tight Junction Assembly Positive Regulation Of Cell Motility	Ubiquinone Biosynthetic Process Menaquinone Biosynthetic Process Ubiquinone Biosynthetic Process Via 3,4-dihydroxy-5-polyprenylbenzoate Vitamin K Biosynthetic Process Vitamin K Metabolic Process Cellular Oxidant Detoxification
Pathways		Tight junction interactions	Metabolism of vitamin K
Drugs
Diseases			Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals
GWAS		Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)	Beard thickness ( 26926045) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010) Weight ( 28552196)
Interacting Genes		77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MFSD5 MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1	38 interacting genes: AHNAK2 ASGR2 BIK CD33 CD53 CD79A CLDN7 CPLX4 CRB3 CREB3L1 CYB5R3 EBP ERGIC3 EVI2A EVI2B FAM209A FCER1G FKBP7 FNDC9 GPR152 HIBADH KCNJ6 LHFPL5 MGST3 MRM3 NCAPH2 PHACTR3 PIGP REEP4 RETREG3 SAR1A SCN3B SLC7A14 SYT1 TMEFF2 TMEM139 TMEM14B VEGFA
Entrez ID		1366	29914
HPRD ID		07633	15487
Ensembl ID		ENSG00000181885	ENSG00000120942
Uniprot IDs		A0A384ME58 F5H496 O95471	Q9Y5Z9
PDB IDs
Enriched GO Terms of Interacting Partners?
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