Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CLDN7 and CLN6
Data Source:
BioGRID
(two hybrid)
CLDN7
CLN6
Description
claudin 7
CLN6 transmembrane ER protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Nucleolus
Early Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Membrane Raft
Molecular Function
Structural Molecule Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Cell Adhesion Molecule Binding
Protein Binding
Lysophosphatidic Acid Binding
Protein Homodimerization Activity
Sulfatide Binding
Biological Process
Cell Adhesion
Negative Regulation Of Cell Adhesion
Positive Regulation Of Cell Population Proliferation
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Apoptotic Process
Response To Ethanol
Bicellular Tight Junction Assembly
Positive Regulation Of Cell Motility
Ganglioside Metabolic Process
Lysosome Organization
Lysosomal Lumen Acidification
Visual Perception
Cholesterol Metabolic Process
Protein Catabolic Process
Glycosaminoglycan Metabolic Process
Locomotion Involved In Locomotory Behavior
Cellular Macromolecule Catabolic Process
Positive Regulation Of Proteolysis
Pathways
Tight junction interactions
Drugs
Diseases
Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS
Birth weight (
31043758
27680694
)
FEV1 (
30804560
)
Lung function (FVC) (
30804560
)
Multiple sclerosis (
31604244
)
Offspring birth weight (
31043758
)
Major depressive disorder (
23377640
)
Restless legs syndrome (
29029846
)
Interacting Genes
77 interacting genes:
AIG1
ANKRD46
APOD
AQP2
ASGR1
BCL2L2
BET1
BMP10
C3orf52
CD53
CD72
CLN6
CMTM5
CNIH1
COL4A5
CXCL16
CXCL9
CYB561A3
CYB561D2
CYB5B
CYBC1
EDDM3B
EMP3
EPCAM
ERG28
ERMP1
FAXDC2
FXYD6
GIMAP5
GLP1R
GPR37L1
HGD
IGFBP5
ITM2A
JAGN1
LAT
LEPROTL1
LPAR3
LSMEM2
MAL
MALL
MFSD5
MS4A13
NDUFB11
NIPAL4
NKG7
OLFM4
PGAP2
PLN
RHOXF2
RPRM
RTP2
SCAMP4
SCARF1
SEC22B
SERTM1
SLC38A7
SYNE4
TJP1
TMEM100
TMEM11
TMEM128
TMEM140
TMEM147
TMEM44
TMEM60
TMEM97
TNF
TRARG1
TSPAN33
UBIAD1
UNC93B1
UPK1B
UPK2
VAMP3
VAMP5
VSTM1
26 interacting genes:
ARL13B
CD79A
CISD2
CLDN7
CLEC10A
CPLX4
CREB3L1
CYBC1
EBAG9
EVI2B
FAM209A
FNDC9
GJA8
GORAB
KIR2DL3
LIME1
LMNA
LRRC25
RIC3
SLC22A23
SLC30A4
STX1A
TEX264
TMEM139
TMEM237
TMPRSS2
Entrez ID
1366
54982
HPRD ID
07633
05991
Ensembl ID
ENSG00000181885
ENSG00000128973
Uniprot IDs
A0A384ME58
F5H496
O95471
A0A024R601
Q9NWW5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?