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MIEF2 and SYP
Data Source:
BioGRID
(two hybrid)
MIEF2
SYP
Description
mitochondrial elongation factor 2
synaptophysin
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Peroxisome
Integral Component Of Membrane
Synaptic Vesicle
Integral Component Of Synaptic Vesicle Membrane
Synaptic Vesicle Membrane
Neuromuscular Junction
Presynaptic Membrane
Neuron Projection
Terminal Bouton
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone
Excitatory Synapse
Schaffer Collateral - CA1 Synapse
Molecular Function
Protein Binding
Protein Binding
Cholesterol Binding
Syntaxin-1 Binding
SH2 Domain Binding
Identical Protein Binding
Protein Self-association
Biological Process
Dynamin Family Protein Polymerization Involved In Mitochondrial Fission
Mitochondrion Organization
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Endocytosis
Synaptic Vesicle Maturation
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Short-term Neuronal Synaptic Plasticity
Synaptic Vesicle Endocytosis
Synaptic Vesicle Membrane Organization
Cellular Response To Organic Substance
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Opioid Receptor Signaling Pathway
Pathways
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Change in neurofilament light levels (
31295725
)
Interacting Genes
30 interacting genes:
AGTRAP
ARFIP2
ARL6IP1
ATP5PF
CIDEA
DNM1L
FAM114A2
FAM25A
FAM25C
FAM25G
FKBP7
GSG1
HSD17B13
LIME1
MDK
NCALD
NCS1
PRB2
PSMF1
RABAC1
REEP6
RHBDD2
SFT2D1
SYP
TMEM239
UBQLN1
UBQLN2
UBQLN4
YIF1A
ZNF628
41 interacting genes:
AP1G1
ARFIP2
CAND2
CD160
DIABLO
FARS2
GAB1
GDNF
GRB2
HSFX1
HSFX2
JOSD2
LNPK
MIEF1
MIEF2
MRM1
MRRF
MTERF3
MYG1
NDRG4
PBX3
PITPNC1
PLIN3
PNKP
PPIF
PTCD1
PTPN9
RBFA
SH3GLB1
SIAH1
SIAH2
SMG9
SNX1
SPG21
SSX5
STARD4
THAP4
TUFM
VAMP2
WDFY2
WIPI2
Entrez ID
125170
6855
HPRD ID
18074
02435
Ensembl ID
ENSG00000177427
ENSG00000102003
Uniprot IDs
Q96C03
P08247
PDB IDs
5WP9
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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