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SYP and MRRF
Data Source:
BioGRID
(two hybrid)
SYP
MRRF
Description
synaptophysin
mitochondrial ribosome recycling factor
Image
No pdb structure
GO Annotations
Cellular Component
Synaptic Vesicle
Integral Component Of Synaptic Vesicle Membrane
Synaptic Vesicle Membrane
Neuromuscular Junction
Presynaptic Membrane
Neuron Projection
Terminal Bouton
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone
Excitatory Synapse
Schaffer Collateral - CA1 Synapse
Mitochondrion
Mitochondrial Matrix
Molecular Function
Protein Binding
Cholesterol Binding
Syntaxin-1 Binding
SH2 Domain Binding
Identical Protein Binding
Protein Self-association
Protein Binding
Ribosomal Large Subunit Binding
Biological Process
Endocytosis
Synaptic Vesicle Maturation
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Short-term Neuronal Synaptic Plasticity
Synaptic Vesicle Endocytosis
Synaptic Vesicle Membrane Organization
Cellular Response To Organic Substance
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Opioid Receptor Signaling Pathway
Translation
Ribosome Disassembly
Mitochondrial Translational Termination
Pathways
Mitochondrial translation termination
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Interacting Genes
41 interacting genes:
AP1G1
ARFIP2
CAND2
CD160
DIABLO
FARS2
GAB1
GDNF
GRB2
HSFX1
HSFX2
JOSD2
LNPK
MIEF1
MIEF2
MRM1
MRRF
MTERF3
MYG1
NDRG4
PBX3
PITPNC1
PLIN3
PNKP
PPIF
PTCD1
PTPN9
RBFA
SH3GLB1
SIAH1
SIAH2
SMG9
SNX1
SPG21
SSX5
STARD4
THAP4
TUFM
VAMP2
WDFY2
WIPI2
10 interacting genes:
AGTRAP
APP
BANP
CMTM5
FAM9B
FHL3
KRT40
SYP
WIPI2
ZNF408
Entrez ID
6855
92399
HPRD ID
02435
06856
Ensembl ID
ENSG00000102003
ENSG00000148187
Uniprot IDs
P08247
Q96E11
PDB IDs
6NU2
6ZS9
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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