SYP and PITPNC1

Data Source:
BioGRID (two hybrid)

		SYP	PITPNC1
Description		synaptophysin	phosphatidylinositol transfer protein cytoplasmic 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Neuron Projection Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Excitatory Synapse Schaffer Collateral - CA1 Synapse	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Cholesterol Binding Syntaxin-1 Binding SH2 Domain Binding Identical Protein Binding Protein Self-association	Protein Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Phosphatidic Acid Binding Phosphatidylglycerol Binding Phosphatidic Acid Transfer Activity
	Biological Process	Endocytosis Synaptic Vesicle Maturation Regulation Of Neuronal Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Endocytosis Synaptic Vesicle Membrane Organization Cellular Response To Organic Substance Regulation Of Synaptic Vesicle Exocytosis Regulation Of Opioid Receptor Signaling Pathway	Signal Transduction Phospholipid Transport Intermembrane Lipid Transfer
Pathways
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS			Blood urea nitrogen levels ( 31152163 29403010) Body size at age 10 ( 32376654) Chronic central serous retinopathy ( 30073298) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Pulmonary function ( 23932459) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum immune biomarker levels ( 32066700) Type 2 diabetes ( 32499647)
Interacting Genes		41 interacting genes: AP1G1 ARFIP2 CAND2 CD160 DIABLO FARS2 GAB1 GDNF GRB2 HSFX1 HSFX2 JOSD2 LNPK MIEF1 MIEF2 MRM1 MRRF MTERF3 MYG1 NDRG4 PBX3 PITPNC1 PLIN3 PNKP PPIF PTCD1 PTPN9 RBFA SH3GLB1 SIAH1 SIAH2 SMG9 SNX1 SPG21 SSX5 STARD4 THAP4 TUFM VAMP2 WDFY2 WIPI2	14 interacting genes: AGTRAP ANKS6 CACFD1 CMTM5 DGAT2L6 GSG1 HTATIP2 KATNAL1 MAL2 REEP5 SCAMP5 SMPD2 SYP TNFRSF10D
Entrez ID		6855	26207
HPRD ID		02435	05504
Ensembl ID		ENSG00000102003	ENSG00000154217
Uniprot IDs		P08247	A0A0C4DGP0 Q9UKF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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