MIEF2 and CIDEA

Data Source:
BioGRID (two hybrid)

		MIEF2	CIDEA
Description		mitochondrial elongation factor 2	cell death inducing DFFA like effector a
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Membrane	Nucleus Cytoplasm Mitochondrion Mitochondrial Envelope Lipid Droplet Cytosol
	Molecular Function	Protein Binding	Protein Homodimerization Activity
	Biological Process	Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane	Temperature Homeostasis Negative Regulation Of Cytokine Production Lipid Metabolic Process Apoptotic Process Cell Death Positive Regulation Of Sequestering Of Triglyceride Lipid Storage Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Lipid Droplet Organization Response To Stilbenoid Regulation Of Apoptotic Process Negative Regulation Of Lipid Catabolic Process Cellular Response To Cold Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Apoptotic DNA Fragmentation
Pathways			Lipid particle organization
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297)
Interacting Genes		30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628	5 interacting genes: CIDEB CIDEC MIEF2 UCP1 ZBTB16
Entrez ID		125170	1149
HPRD ID		18074	08380
Ensembl ID		ENSG00000177427	ENSG00000176194
Uniprot IDs		Q96C03	B3KVA2 O60543 Q8N5P9
PDB IDs		5WP9	2EEL
Enriched GO Terms of Interacting Partners?
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