CCR8 and TPST1

Data Source:
HPRD (in vitro)

		CCR8	TPST1
Description		C-C motif chemokine receptor 8	tyrosylprotein sulfotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Golgi Membrane
	Molecular Function	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity
	Biological Process	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Peptidyl-tyrosine Sulfation Inflammatory Response Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)	Blood protein levels ( 30072576 29875488) Gout ( 22179738)
Interacting Genes		19 interacting genes: ATP2A1 CCL1 CCL16 CCL17 CCL4 EI24 ERGIC3 GABBR1 GABRD NAGPA PAQR6 PLEKHB1 RTN3 SPNS1 SPP1 THY1 TPST1 TPST2 UCKL1	6 interacting genes: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG
Entrez ID		1237	8460
HPRD ID		03497	07216
Ensembl ID		ENSG00000179934	ENSG00000169902
Uniprot IDs		P51685	A0A024RDK9 O60507
PDB IDs			5WRI 5WRJ
Enriched GO Terms of Interacting Partners?
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