CCR8 and TPST2

Data Source:
HPRD (in vitro)

		CCR8	TPST2
Description		C-C motif chemokine receptor 8	tyrosylprotein sulfotransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity
	Biological Process	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Peptidyl-tyrosine Sulfation Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)	Anti-saccade response ( 29064472) Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: ATP2A1 CCL1 CCL16 CCL17 CCL4 EI24 ERGIC3 GABBR1 GABRD NAGPA PAQR6 PLEKHB1 RTN3 SPNS1 SPP1 THY1 TPST1 TPST2 UCKL1	5 interacting genes: CCR1 CCR8 CMKLR1 GPR1 SELPLG
Entrez ID		1237	8459
HPRD ID		03497	07217
Ensembl ID		ENSG00000179934	ENSG00000128294
Uniprot IDs		P51685	A0A024R1G9 O60704
PDB IDs			3AP1 3AP2 3AP3
Enriched GO Terms of Interacting Partners?
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