CCR8 and CCL16

Data Source:
HPRD (in vivo, in vitro)

		CCR8	CCL16
Description		C-C motif chemokine receptor 8	C-C motif chemokine ligand 16
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Binding Chemokine Activity Chemoattractant Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Monocyte Chemotaxis Chemotaxis Inflammatory Response Cell Communication G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Positive Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)	Blood protein levels ( 29875488 28240269) Initial pursuit acceleration ( 29064472)
Interacting Genes		19 interacting genes: ATP2A1 CCL1 CCL16 CCL17 CCL4 EI24 ERGIC3 GABBR1 GABRD NAGPA PAQR6 PLEKHB1 RTN3 SPNS1 SPP1 THY1 TPST1 TPST2 UCKL1	6 interacting genes: CCL5 CCR1 CCR5 CCR8 HRH4 UBQLN2
Entrez ID		1237	6360
HPRD ID		03497	03233
Ensembl ID		ENSG00000179934	ENSG00000275152
Uniprot IDs		P51685	O15467
PDB IDs			5LTL
Enriched GO Terms of Interacting Partners?
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