TPST1 and SELPLG

Data Source:
HPRD (in vitro)

		TPST1	SELPLG
Description		tyrosylprotein sulfotransferase 1	selectin P ligand
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Golgi Membrane	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft
	Molecular Function	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity	Virus Receptor Activity Signaling Receptor Binding Protein Binding
	Biological Process	Peptidyl-tyrosine Sulfation Inflammatory Response Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6
Pathways		Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Gout ( 22179738)	Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)
Interacting Genes		6 interacting genes: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG	14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN
Entrez ID		8460	6404
HPRD ID		07216	02845
Ensembl ID		ENSG00000169902	ENSG00000110876
Uniprot IDs		A0A024RDK9 O60507	Q14242
PDB IDs		5WRI 5WRJ	1G1S
Enriched GO Terms of Interacting Partners?
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