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DDIT4L and BAG4
Data Source:
BioGRID
(two hybrid)
DDIT4L
BAG4
Description
DNA damage inducible transcript 4 like
BAG cochaperone 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Molecular Function
Protein Binding
Adenyl-nucleotide Exchange Factor Activity
RNA Binding
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Chaperone Binding
Biological Process
Negative Regulation Of Signal Transduction
Protein Folding
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Adhesion
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of MRNA Modification
Ruffle Assembly
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways
Regulation of HSF1-mediated heat shock response
Signaling by FGFR1 in disease
TNF signaling
Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Nose size (
27182965
)
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
28991256
29483656
)
Interacting Genes
154 interacting genes:
ABCB11
ACY3
AFMID
AIDA
AKT1
ARPIN
BAG4
BANF2
BCL2L14
BID
C14orf119
C18orf25
C19orf25
C5orf22
CABP5
CALCOCO2
CALM1
CALM2
CALM3
CATIP
CCNK
CDA
CDKN2D
CDPF1
CHMP1A
CLIC3
CLK2
CLK3
CPNE7
CRLF3
CRYBB1
DBI
DNPH1
DUSP23
DUSP29
EIF4A3
EIF4EBP1
EIF4H
EPHB6
EXOSC1
EXOSC5
EXOSC8
FAAP20
FADD
FHIT
FHL2
FKBP6
FLNA
GADD45G
GEMIN6
GPKOW
GRB2
GUCA1A
HDAC7
HMG20A
HSPB7
IL36RN
IMPDH1
KANK2
KCTD9
KDM8
KRT34
KRTAP5-6
LENG1
LGALS14
LGALSL
LMO1
LRATD2
LSM3
LSM5
LSM7
MAP3K7CL
MAPRE2
MAPRE3
MEMO1
MIEN1
MKRN3
MLX
MORF4L2
MT1M
MYG1
MYLIP
NAA10
NAV1
NEK6
NGB
NHLRC4
NME7
NQO2
NR2C2AP
NUDT2
NUDT22
NXT2
PARVG
PCBP3
PDE4C
PFKFB1
PLSCR4
PM20D2
PMVK
PPCDC
PPIL1
PPP1R27
PRKAB2
PRPF40A
PSMA1
PSMB9
PTS
PUF60
RAB32
RFC5
RFPL3
RPIA
RPL22
RPRD1B
SCOC
SEC22A
SEPTIN1
SEPTIN3
SEPTIN5
SH3BGRL3
SNRPA
SNRPG
SREK1IP1
STK16
STK4
SULT2B1
TBC1D22B
TCL1A
TCP11L1
TEKT4
TEX14
TFPT
TNS2
TOLLIP
TRIM73
TSEN15
TSSK3
TTC5
TXN
TXNL4A
TYW3
UBASH3A
UBTFL1
VBP1
VCX2
YES1
YOD1
YPEL5
ZBED8
ZNF593
ZNF76
ZNF765
ZSCAN23
117 interacting genes:
ABI2
ACOT7
ADAMTSL4
ALG13
APOBEC1
ARID5A
ATAD2
ATP23
BAP1
BCAS3
BCL2
BCL6B
BEX1
BLZF1
C3orf38
CASP2
CASZ1
CBFA2T2
CCL5
DDIT4L
DIRAS3
DZIP3
EFEMP1
EPSTI1
ERRFI1
FAM214B
FAM222B
FARS2
FTH1
FYN
GLCE
GPANK1
GPS2
GRAP2
HOXA1
HSPA1A
HSPA1B
HSPA1L
HSPA2
HSPA6
HSPA8
IL13RA2
IL24
IST1
ITIH5
KCTD6
KCTD7
KIF5B
KLK5
KLK7
KLK9
KRTAP13-1
KRTAP13-4
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP6-3
LASP1
LRATD2
LYPD3
MAGED1
MEI4
MRC2
MTA3
MYOZ1
MYOZ3
MYPOP
NAT2
ODF1
ODF3L1
P4HA3
PDCD6
PDLIM2
PEF1
PGRMC2
PHF19
PLAC8
PPIL6
PPP1R32
PRDM14
PSMB5
PYCR3
RAMAC
RASL10B
RHOBTB2
RNF20
RPL22
RUNX1
SAMD4A
SAXO1
SCGB3A1
SH3RF2
SIAH1
SNRPB
SNRPC
SS18L1
SUOX
TBC1D3B
TBC1D3G
TBC1D7
TCL1B
TEKT5
TFAP2D
THRSP
TINAGL1
TLE5
TNFRSF1A
TNFRSF25
TRAPPC6A
TSG101
UNKL
USP22
VPS37C
ZBTB45
ZBTB5
ZIM2
Entrez ID
115265
9530
HPRD ID
09663
04861
Ensembl ID
ENSG00000145358
ENSG00000156735
Uniprot IDs
Q96D03
O95429
PDB IDs
1M62
1M7K
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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