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DDIT4L and CCNK
Data Source:
BioGRID
(two hybrid)
DDIT4L
CCNK
Description
DNA damage inducible transcript 4 like
cyclin K
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Molecular Function
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Biological Process
Negative Regulation Of Signal Transduction
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Nose size (
27182965
)
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
154 interacting genes:
ABCB11
ACY3
AFMID
AIDA
AKT1
ARPIN
BAG4
BANF2
BCL2L14
BID
C14orf119
C18orf25
C19orf25
C5orf22
CABP5
CALCOCO2
CALM1
CALM2
CALM3
CATIP
CCNK
CDA
CDKN2D
CDPF1
CHMP1A
CLIC3
CLK2
CLK3
CPNE7
CRLF3
CRYBB1
DBI
DNPH1
DUSP23
DUSP29
EIF4A3
EIF4EBP1
EIF4H
EPHB6
EXOSC1
EXOSC5
EXOSC8
FAAP20
FADD
FHIT
FHL2
FKBP6
FLNA
GADD45G
GEMIN6
GPKOW
GRB2
GUCA1A
HDAC7
HMG20A
HSPB7
IL36RN
IMPDH1
KANK2
KCTD9
KDM8
KRT34
KRTAP5-6
LENG1
LGALS14
LGALSL
LMO1
LRATD2
LSM3
LSM5
LSM7
MAP3K7CL
MAPRE2
MAPRE3
MEMO1
MIEN1
MKRN3
MLX
MORF4L2
MT1M
MYG1
MYLIP
NAA10
NAV1
NEK6
NGB
NHLRC4
NME7
NQO2
NR2C2AP
NUDT2
NUDT22
NXT2
PARVG
PCBP3
PDE4C
PFKFB1
PLSCR4
PM20D2
PMVK
PPCDC
PPIL1
PPP1R27
PRKAB2
PRPF40A
PSMA1
PSMB9
PTS
PUF60
RAB32
RFC5
RFPL3
RPIA
RPL22
RPRD1B
SCOC
SEC22A
SEPTIN1
SEPTIN3
SEPTIN5
SH3BGRL3
SNRPA
SNRPG
SREK1IP1
STK16
STK4
SULT2B1
TBC1D22B
TCL1A
TCP11L1
TEKT4
TEX14
TFPT
TNS2
TOLLIP
TRIM73
TSEN15
TSSK3
TTC5
TXN
TXNL4A
TYW3
UBASH3A
UBTFL1
VBP1
VCX2
YES1
YOD1
YPEL5
ZBED8
ZNF593
ZNF76
ZNF765
ZSCAN23
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
Entrez ID
115265
8812
HPRD ID
09663
10352
Ensembl ID
ENSG00000145358
ENSG00000090061
Uniprot IDs
Q96D03
A0A024R6K1
O75909
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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