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DTX2 and NCS1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DTX2
NCS1
Description
deltex E3 ubiquitin ligase 2
neuronal calcium sensor 1
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nuclear Membrane
Cytoplasm
Golgi Apparatus
Plasma Membrane
Postsynaptic Density
Dendrite
Dense Core Granule
Intracellular Membrane-bounded Organelle
Calyx Of Held
Perinuclear Region Of Cytoplasm
Glutamatergic Synapse
Presynaptic Cytosol
Postsynaptic Cytosol
Molecular Function
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Magnesium Ion Binding
Voltage-gated Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Protein Kinase Binding
Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
Biological Process
Notch Signaling Pathway
Protein Ubiquitination
Regulation Of Neuron Projection Development
Positive Regulation Of Exocytosis
Phosphatidylinositol-mediated Signaling
Calcium Ion Transmembrane Transport
Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Activated NOTCH1 Transmits Signal to the Nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Tuberculosis (
30713548
)
Interacting Genes
131 interacting genes:
ABHD11
ABHD16A
ALKBH4
ANAPC11
ANTKMT
ARID5A
ARMC7
ARNT2
BCL2L11
BICRAL
BOLA2-SMG1P6
C10orf55
C11orf1
C19orf54
C1orf94
C20orf85
C22orf39
CCDC57
CLPP
COA6
COQ8A
DAZAP2
DOK3
DTX1
DTX3
ECM1
ECSIT
EIF4ENIF1
EIF4G1
EYA2
FAM168A
FCRL4
FHL2
FHL5
FOXI1
FTO
GLYCTK
GOLGA2
HDC
HGS
HLX
HOXA1
HOXB2
HOXD12
HPCA
HPCAL1
HPCAL4
HSFY1
HSFY2
IKZF3
KANK2
KLC3
KLHDC7B
KRTAP11-1
KRTAP13-3
KRTAP15-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP7-1
KRTAP8-1
LASP1
LNX1
LRP2BP
MBD3L1
MDC1
MED19
MSS51
MVP
MXRA8
NCALD
NCS1
NHLRC4
NIF3L1
NME4
NOTCH1
OIP5
PARP1
PAX5
PLEKHF2
PLEKHG4
PLSCR1
POGZ
PPP1R32
PRR32
PRR34
PSMB4
QARS1
RBM11
RBPMS
RFX6
RHOXF2
RIMBP3
RUNX1
RUSC1
SEC22A
SEC23A
SEC23B
SEPSECS
SLC22A18AS
SOHLH1
SPAG8
SPG21
STX12
SUMO1
TBX15
TEKT5
TENT2
TMEM42
TRIB3
TRIM35
TRIM54
TRIP13
TRIP6
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBQLN4
USP54
VGLL3
VSNL1
ZNF34
ZNF503
ZNF620
ZNF641
ZNF764
ZNF774
ZNF85
27 interacting genes:
C1QTNF2
CDSN
CEP89
CREM
CTAG1A
CTAG1B
DRD2
DRD3
DRD5
DTX2
FZD7
GRK2
IL1RAPL1
KCND2
LY6G6D
MEOX2
MIEF2
NBL1
OXER1
PI4KB
PRDM4
RNASEH1
SFTPA2
SIGLEC9
SPP1
SPRED2
ZC3H10
Entrez ID
113878
23413
HPRD ID
16841
04500
Ensembl ID
ENSG00000091073
ENSG00000107130
Uniprot IDs
Q86UW9
A0A024R8B2
P62166
PDB IDs
6IR0
6Y22
6Y2X
6Y3J
1G8I
2LCP
4GUK
5O9S
6QI4
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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