NCS1 and C1QTNF2

Data Source:
BioGRID (two hybrid)

		NCS1	C1QTNF2
Description		neuronal calcium sensor 1	C1q and TNF related 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol	Extracellular Region Collagen Trimer
	Molecular Function	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels	Protein Binding
	Biological Process	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis	Regulation Of Lipid Metabolic Process
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)	Weight loss (gastric bypass surgery) ( 23643386)
Interacting Genes		27 interacting genes: C1QTNF2 CDSN CEP89 CREM CTAG1A CTAG1B DRD2 DRD3 DRD5 DTX2 FZD7 GRK2 IL1RAPL1 KCND2 LY6G6D MEOX2 MIEF2 NBL1 OXER1 PI4KB PRDM4 RNASEH1 SFTPA2 SIGLEC9 SPP1 SPRED2 ZC3H10	24 interacting genes: ANKRD11 BANP C1orf109 CHIC2 GPANK1 HPCA HPCAL1 KCNIP3 KLHL12 LCK LGALS14 MTX2 NCALD NCS1 NOL4 P4HA3 PHOSPHO2 TCEANC TIMM8A TRIM54 UBQLN1 UBQLN2 USP20 VSNL1
Entrez ID		23413	114898
HPRD ID		04500	12715
Ensembl ID		ENSG00000107130	ENSG00000145861
Uniprot IDs		A0A024R8B2 P62166	A0A3B0INC0 A0A499FIM1 Q9BXJ5
PDB IDs		1G8I 2LCP 4GUK 5O9S 6QI4
Enriched GO Terms of Interacting Partners?
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