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DTX2 and MED19
Data Source:
BioGRID
(two hybrid)
DTX2
MED19
Description
deltex E3 ubiquitin ligase 2
mediator complex subunit 19
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nuclear Membrane
Mediator Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Transcription Coregulator Activity
Protein Binding
Transcription Factor Binding
Biological Process
Notch Signaling Pathway
Protein Ubiquitination
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Activated NOTCH1 Transmits Signal to the Nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Reticulocyte count (
32888494
)
Schizophrenia (
28991256
25056061
29483656
)
Interacting Genes
131 interacting genes:
ABHD11
ABHD16A
ALKBH4
ANAPC11
ANTKMT
ARID5A
ARMC7
ARNT2
BCL2L11
BICRAL
BOLA2-SMG1P6
C10orf55
C11orf1
C19orf54
C1orf94
C20orf85
C22orf39
CCDC57
CLPP
COA6
COQ8A
DAZAP2
DOK3
DTX1
DTX3
ECM1
ECSIT
EIF4ENIF1
EIF4G1
EYA2
FAM168A
FCRL4
FHL2
FHL5
FOXI1
FTO
GLYCTK
GOLGA2
HDC
HGS
HLX
HOXA1
HOXB2
HOXD12
HPCA
HPCAL1
HPCAL4
HSFY1
HSFY2
IKZF3
KANK2
KLC3
KLHDC7B
KRTAP11-1
KRTAP13-3
KRTAP15-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP7-1
KRTAP8-1
LASP1
LNX1
LRP2BP
MBD3L1
MDC1
MED19
MSS51
MVP
MXRA8
NCALD
NCS1
NHLRC4
NIF3L1
NME4
NOTCH1
OIP5
PARP1
PAX5
PLEKHF2
PLEKHG4
PLSCR1
POGZ
PPP1R32
PRR32
PRR34
PSMB4
QARS1
RBM11
RBPMS
RFX6
RHOXF2
RIMBP3
RUNX1
RUSC1
SEC22A
SEC23A
SEC23B
SEPSECS
SLC22A18AS
SOHLH1
SPAG8
SPG21
STX12
SUMO1
TBX15
TEKT5
TENT2
TMEM42
TRIB3
TRIM35
TRIM54
TRIP13
TRIP6
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBQLN4
USP54
VGLL3
VSNL1
ZNF34
ZNF503
ZNF620
ZNF641
ZNF764
ZNF774
ZNF85
19 interacting genes:
APP
DCK
DHRS7B
DTX2
GRB2
HLCS
KANK2
MED17
MED27
MED31
MED8
MED9
MSX1
NEDD9
NFKBIA
OSTF1
RADIL
RIPPLY1
ZNF76
Entrez ID
113878
219541
HPRD ID
16841
17477
Ensembl ID
ENSG00000091073
ENSG00000156603
Uniprot IDs
Q86UW9
A0JLT2
PDB IDs
6IR0
6Y22
6Y2X
6Y3J
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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