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NCS1 and DRD3
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid, in vivo)
NCS1
DRD3
Description
neuronal calcium sensor 1
dopamine receptor D3
Image
GO Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Plasma Membrane
Postsynaptic Density
Dendrite
Dense Core Granule
Intracellular Membrane-bounded Organelle
Calyx Of Held
Perinuclear Region Of Cytoplasm
Glutamatergic Synapse
Presynaptic Cytosol
Postsynaptic Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Endocytic Vesicle
Cell Projection
Apical Part Of Cell
Glutamatergic Synapse
GABA-ergic Synapse
Integral Component Of Postsynaptic Density Membrane
Molecular Function
Magnesium Ion Binding
Voltage-gated Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Protein Kinase Binding
Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go
G Protein-coupled Receptor Activity
Protein Binding
Protein Domain Specific Binding
D1 Dopamine Receptor Binding
Biological Process
Regulation Of Neuron Projection Development
Positive Regulation Of Exocytosis
Phosphatidylinositol-mediated Signaling
Calcium Ion Transmembrane Transport
Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Regulation Of Synaptic Vesicle Exocytosis
Negative Regulation Of Transcription By RNA Polymerase II
Synaptic Transmission, Dopaminergic
G Protein-coupled Receptor Internalization
Cellular Calcium Ion Homeostasis
Autophagy
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Learning Or Memory
Learning
Locomotory Behavior
Positive Regulation Of Cell Population Proliferation
Visual Learning
Regulation Of Dopamine Secretion
Negative Regulation Of Sodium:proton Antiporter Activity
Positive Regulation Of Cytokinesis
Circadian Regulation Of Gene Expression
Response To Histamine
Social Behavior
Gastric Emptying
Positive Regulation Of Renal Sodium Excretion
Response To Cocaine
Dopamine Metabolic Process
Response To Drug
Negative Regulation Of Apoptotic Process
Regulation Of Potassium Ion Transport
Response To Morphine
Regulation Of Circadian Sleep/wake Cycle, Sleep
Response To Ethanol
Negative Regulation Of Blood Pressure
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription By RNA Polymerase II
Acid Secretion
Behavioral Response To Cocaine
Negative Regulation Of Oligodendrocyte Differentiation
Arachidonic Acid Secretion
Negative Regulation Of Protein Secretion
Musculoskeletal Movement, Spinal Reflex Action
Negative Regulation Of Cytosolic Calcium Ion Concentration
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Synaptic Transmission, Glutamatergic
Prepulse Inhibition
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Positive Regulation Of Dopamine Receptor Signaling Pathway
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Regulation Of Locomotion Involved In Locomotory Behavior
Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Negative Regulation Of Voltage-gated Calcium Channel Activity
Pathways
Dopamine receptors
G alpha (i) signalling events
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Ziprasidone
Cabergoline
Ropinirole
Olanzapine
Clozapine
Sulpiride
Loxapine
Remoxipride
Pramipexole
Chlorpromazine
Buspirone
Haloperidol
Amoxapine
Lisuride
Apomorphine
Dopamine
Ergoloid mesylate
Pimozide
Domperidone
Pergolide
Bromocriptine
Quetiapine
Levodopa
Aripiprazole
Chlorprothixene
Paliperidone
Yohimbine
Methotrimeprazine
Iloperidone
Rotigotine
ACP-104
Cariprazine
Mianserin
Asenapine
Amisulpride
Sarizotan
Sumanirole
Captodiame
AS-8112
Blonanserin
Pipamperone
Tianeptine
Dihydro-alpha-ergocryptine
Epicriptine
Pardoprunox
Piribedil
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Tuberculosis (
30713548
)
Chronotype (
30696823
)
Feeling hurt (
29500382
)
Personality dimensions (
23903073
)
Smooth-surface caries (
24556642
)
Interacting Genes
27 interacting genes:
C1QTNF2
CDSN
CEP89
CREM
CTAG1A
CTAG1B
DRD2
DRD3
DRD5
DTX2
FZD7
GRK2
IL1RAPL1
KCND2
LY6G6D
MEOX2
MIEF2
NBL1
OXER1
PI4KB
PRDM4
RNASEH1
SFTPA2
SIGLEC9
SPP1
SPRED2
ZC3H10
16 interacting genes:
CLIC6
DRD1
EEF1B2
EEF1G
EPB41
EPB41L1
EPB41L2
FLNA
GIPC1
GNAI1
GRB2
MPDZ
NCK1
NCS1
RDX
USP48
Entrez ID
23413
1814
HPRD ID
04500
00540
Ensembl ID
ENSG00000107130
ENSG00000151577
Uniprot IDs
A0A024R8B2
P62166
A1A4V4
A8K8E4
E9PCM4
P35462
X5D2G4
PDB IDs
1G8I
2LCP
4GUK
5O9S
6QI4
3PBL
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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