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DTX2 and UBE2D4
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid, affinity chromatography technology, two hybrid)
HPRD
(two hybrid)
DTX2
UBE2D4
Description
deltex E3 ubiquitin ligase 2
ubiquitin conjugating enzyme E2 D4 (putative)
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nuclear Membrane
Ubiquitin Ligase Complex
Nucleus
Molecular Function
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Notch Signaling Pathway
Protein Ubiquitination
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Activated NOTCH1 Transmits Signal to the Nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes
131 interacting genes:
ABHD11
ABHD16A
ALKBH4
ANAPC11
ANTKMT
ARID5A
ARMC7
ARNT2
BCL2L11
BICRAL
BOLA2-SMG1P6
C10orf55
C11orf1
C19orf54
C1orf94
C20orf85
C22orf39
CCDC57
CLPP
COA6
COQ8A
DAZAP2
DOK3
DTX1
DTX3
ECM1
ECSIT
EIF4ENIF1
EIF4G1
EYA2
FAM168A
FCRL4
FHL2
FHL5
FOXI1
FTO
GLYCTK
GOLGA2
HDC
HGS
HLX
HOXA1
HOXB2
HOXD12
HPCA
HPCAL1
HPCAL4
HSFY1
HSFY2
IKZF3
KANK2
KLC3
KLHDC7B
KRTAP11-1
KRTAP13-3
KRTAP15-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP7-1
KRTAP8-1
LASP1
LNX1
LRP2BP
MBD3L1
MDC1
MED19
MSS51
MVP
MXRA8
NCALD
NCS1
NHLRC4
NIF3L1
NME4
NOTCH1
OIP5
PARP1
PAX5
PLEKHF2
PLEKHG4
PLSCR1
POGZ
PPP1R32
PRR32
PRR34
PSMB4
QARS1
RBM11
RBPMS
RFX6
RHOXF2
RIMBP3
RUNX1
RUSC1
SEC22A
SEC23A
SEC23B
SEPSECS
SLC22A18AS
SOHLH1
SPAG8
SPG21
STX12
SUMO1
TBX15
TEKT5
TENT2
TMEM42
TRIB3
TRIM35
TRIM54
TRIP13
TRIP6
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBQLN4
USP54
VGLL3
VSNL1
ZNF34
ZNF503
ZNF620
ZNF641
ZNF764
ZNF774
ZNF85
109 interacting genes:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
H3C1
H4C1
IKBKG
INCA1
ITCH
LNX1
LRSAM1
MAGEA11
MAP3K1
MARCHF3
MDM2
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
POLR2E
PRKN
RBCK1
RCHY1
REL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF216
RNF26
RNF31
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
STUB1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM62
TRIM8
UBA1
UBC
UBE4A
UBOX5
UBTD1
UBTD2
UFM1
UHRF2
UVSSA
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
113878
51619
HPRD ID
16841
14242
Ensembl ID
ENSG00000091073
ENSG00000078967
Uniprot IDs
Q86UW9
A0A024RA90
Q9UQL0
Q9Y2X8
PDB IDs
6IR0
6Y22
6Y2X
6Y3J
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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