EXOC3 and EXOC2

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		EXOC3	EXOC2
Description		exocyst complex component 3	exocyst complex component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Golgi Apparatus Cytosol Growth Cone Midbody Secretory Granule Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm	Exocyst Cytosol Plasma Membrane Membrane Flemming Body
	Molecular Function	SNARE Binding Protein Binding Cadherin Binding	Protein Binding Protein Kinase Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Exocytosis Protein Transport Exocyst Localization	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Hypospadias ( 25108383) Red blood cell count ( 32888494) Ulcerative colitis ( 21297633)	Alopecia areata ( 25608926) Asthma (childhood onset) ( 31036433) Basal cell carcinoma ( 21700618 27539887) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Blond vs. brown/black hair color ( 30531825) Blood metabolite levels ( 31502714) Brown vs. black hair color ( 30531825) Dental caries ( 23064961) Diffuse large B cell lymphoma ( 25261932) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998 29785010 31959993 30054594) Limited cutaneous systemic scleroderma ( 29293537) Lung cancer in ever smokers ( 28604730) Male-pattern baldness ( 28196072) Medication use (antiglaucoma preparations and miotics) ( 31015401) Melanoma ( 28212542) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Non-melanoma skin cancer ( 23548203) Optic cup area ( 31798171) Primary central nervous system lymphoma ( 31102405) Psoriasis ( 25903422 25574825 23143594) Schizophrenia ( 22885689) Sum eosinophil basophil counts ( 27863252) Tanning ( 19340012) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) WaldenstrÃ¶m macroglobulinemia / lymphoplasmacytic lymphoma ( 30305637)
Interacting Genes		10 interacting genes: APP BIRC6 BUB3 EXOC2 FSD2 GMCL1 MLH1 PPP1R12C RALA VAMP2	9 interacting genes: CDKN2A ESX1 EXOC3 EXOC7 EXOC8 RALA RANBP9 SERGEF VPS53
Entrez ID		11336	55770
HPRD ID		09738	11544
Ensembl ID		ENSG00000180104	ENSG00000112685
Uniprot IDs		A0A024QYZ6 O60645 Q69YP2	A0A024QZT2 Q96KP1
PDB IDs
Enriched GO Terms of Interacting Partners?
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