EXOC2 and EXOC7

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		EXOC2	EXOC7
Description		exocyst complex component 2	exocyst complex component 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Flemming Body	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Entry Of Bacterium Into Host Cell	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Asthma (childhood onset) ( 31036433) Basal cell carcinoma ( 21700618 27539887) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Blond vs. brown/black hair color ( 30531825) Blood metabolite levels ( 31502714) Brown vs. black hair color ( 30531825) Dental caries ( 23064961) Diffuse large B cell lymphoma ( 25261932) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998 29785010 31959993 30054594) Limited cutaneous systemic scleroderma ( 29293537) Lung cancer in ever smokers ( 28604730) Male-pattern baldness ( 28196072) Medication use (antiglaucoma preparations and miotics) ( 31015401) Melanoma ( 28212542) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Non-melanoma skin cancer ( 23548203) Optic cup area ( 31798171) Primary central nervous system lymphoma ( 31102405) Psoriasis ( 25903422 25574825 23143594) Schizophrenia ( 22885689) Sum eosinophil basophil counts ( 27863252) Tanning ( 19340012) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) WaldenstrÃ¶m macroglobulinemia / lymphoplasmacytic lymphoma ( 30305637)	Body size at age 10 ( 32376654)
Interacting Genes		9 interacting genes: CDKN2A ESX1 EXOC3 EXOC7 EXOC8 RALA RANBP9 SERGEF VPS53	37 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14
Entrez ID		55770	23265
HPRD ID		11544	16292
Ensembl ID		ENSG00000112685	ENSG00000182473
Uniprot IDs		A0A024QZT2 Q96KP1	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs
Enriched GO Terms of Interacting Partners?
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